Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 11/20 | 0.50 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23229440 | 0.92 | PTPN11 (0.46) | PTPN11 | |
| SCHEMBL23209070 | 0.89 | PTPN11 (0.51) | PTPN11 | |
| SCHEMBL23208873 | 0.89 | PTPN11 (0.51) | PTPN11 | |
| SCHEMBL23208806 | 0.89 | PTPN11 (0.51) | PTPN11 | |
| SCHEMBL23209034 | 0.87 | PTPN11 (0.53) | PTPN11DGAT1 | |
| SCHEMBL23208902 | 0.86 | PTPN11 (0.36) | PTPN11DGAT1 | |
| SCHEMBL23208715 | 0.81 | DGAT1 (0.35) | DGAT1EGFR | |
| SCHEMBL23209040 | 0.81 | DGAT1 (0.35) | DGAT1EGFR | |
| SCHEMBL23209044 | 0.81 | DGAT1 (0.35) | DGAT1EGFR | |
| SCHEMBL23209115 | 0.81 | DGAT1 (0.35) | DGAT1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210107908-A1 | PHARMACEUTICAL COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2021-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210107908-A1 | PHARMACEUTICAL COMPOUNDS | MAPT, CYP3A5, SLC5A1 | PTPN11 326/4885DGAT1 4132/4885EGFR 1551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.