Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 7/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.37 |
| ▸ | ATXN2 | Q99700 | 3/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23177311 | 1.00 | MGLL (0.54) | MGLLENPP2ATXN2CYP11B1CYP11B2 | |
| SCHEMBL23210161 | 1.00 | MGLL (0.54) | MGLLENPP2ATXN2CYP11B1CYP11B2 | |
| SCHEMBL23152335 | 1.00 | MGLL (0.54) | MGLLENPP2ATXN2CYP11B1CYP11B2 | |
| SCHEMBL27288738 | 0.94 | MGLL (0.53) | MGLLENPP2ATXN2CYP11B1CYP11B2 | |
| SCHEMBL23152389 | 0.86 | MGLL (0.54) | MGLLENPP2ATXN2 | |
| SCHEMBL23210159 | 0.86 | MGLL (0.54) | MGLLENPP2ATXN2 | |
| SCHEMBL29616710 | 0.86 | MGLL (0.54) | MGLLENPP2ATXN2 | |
| SCHEMBL23152302 | 0.86 | MGLL (0.54) | MGLLENPP2ATXN2 | |
| SCHEMBL23152301 | 0.86 | MGLL (0.54) | MGLLENPP2ATXN2 | |
| SCHEMBL23177381 | 0.86 | MGLL (0.54) | MGLLENPP2ATXN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210107921-A1 | HETEROCYCLIC COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2021-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210107921-A1 | HETEROCYCLIC COMPOUNDS | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, NQO1, CCNY | MGLL 2899/4885ENPP2 1627/4885ATXN2 125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.