Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 7/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.38 |
| ▸ | ATXN2 | Q99700 | 3/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | CCRL2 | O00421 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23177311 | 0.94 | MGLL (0.54) | MGLLENPP2ATXN2CYP11B1CYP11B2 | |
| SCHEMBL23152335 | 0.94 | MGLL (0.54) | MGLLENPP2ATXN2CYP11B1CYP11B2 | |
| SCHEMBL23210288 | 0.94 | MGLL (0.54) | MGLLENPP2ATXN2CYP11B1CYP11B2 | |
| SCHEMBL23210161 | 0.94 | MGLL (0.54) | MGLLENPP2ATXN2CYP11B1CYP11B2 | |
| SCHEMBL27289393 | 0.86 | MGLL (0.49) | MGLLENPP2ATXN2CCRL2 | |
| SCHEMBL23177381 | 0.85 | MGLL (0.54) | MGLLENPP2ATXN2 | |
| SCHEMBL23152302 | 0.85 | MGLL (0.54) | MGLLENPP2ATXN2 | |
| SCHEMBL29616710 | 0.85 | MGLL (0.54) | MGLLENPP2ATXN2 | |
| SCHEMBL23152389 | 0.85 | MGLL (0.54) | MGLLENPP2ATXN2 | |
| SCHEMBL23152301 | 0.85 | MGLL (0.54) | MGLLENPP2ATXN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |