Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MBTPS1 | Q14703 | 6/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5143426 | 0.87 | CTSD (0.55) | L3MBTL1KCNH2CTSDSLC6A2SLC6A4 | |
| SCHEMBL1623585 | 0.87 | CTSD (0.55) | L3MBTL1KCNH2CTSDSLC6A2SLC6A4 | |
| SCHEMBL2727813 | 0.87 | CTSD (0.55) | L3MBTL1KCNH2CTSDSLC6A2SLC6A4 | |
| SCHEMBL16527961 | 0.83 | PYGL (0.46) | RPS6KB1MBTPS1KCNH2CTSDSLC6A2 | |
| SCHEMBL27936852 | 0.82 | CTSD (0.50) | RPS6KB1KCNH2CTSDSLC6A2SLC6A4 | |
| SCHEMBL27936854 | 0.82 | CTSD (0.50) | RPS6KB1KCNH2CTSDSLC6A2SLC6A4 | |
| SCHEMBL21625220 | 0.80 | SLC18A3 (0.50) | RPS6KB1L3MBTL1OPRM1SLC6A2SLC6A4 | |
| SCHEMBL31016686 | 0.80 | SLC18A3 (0.50) | RPS6KB1L3MBTL1OPRM1SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL29057102 | 0.79 | SLC18A3 (0.49) | RPS6KB1L3MBTL1OPRM1SLC6A2SLC6A4 | |
| SCHEMBL18342235 | 0.78 | SLC6A2 (0.60) | KCNH2CTSDSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11623921-B2 | Indole carboxamide compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-04-11 | — | — | US | disclosed |
| US-20210107891-A1 | INDOLE CARBOXAMIDE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2021-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11623921-B2 | Indole carboxamide compounds | BTK, JAK2, BRD4 | RPS6KB1 597/4885L3MBTL1 3589/4885MBTPS1 2752/4885 |
| US-20210107891-A1 | INDOLE CARBOXAMIDE COMPOUNDS | BTK, JAK2, BRD4 | RPS6KB1 597/4885L3MBTL1 3589/4885MBTPS1 2752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.