Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 5/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 5/20 | 0.47 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.42 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.42 |
| ▸ | GRIK4 | Q16099 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7235118 | 0.77 | GRIA1 (0.47) | GRIA1GRIA2GRIA4GRIK5GRIA3 | |
| SCHEMBL16174493 | 0.77 | GRIA1 (0.50) | GRIA1GRIA2GRIA4GRIK5GRIA3 | |
| SCHEMBL22748998 | 0.73 | GRIA1 (0.57) | GRIA1GRIA2GRIA4GRIK5GRIA3 | |
| SCHEMBL7233498 | 0.70 | GRIA1 (0.58) | GRIA1GRIA2GRIA4GRIK5GRIA3 | |
| SCHEMBL11708335 | 0.69 | GRIA1 (0.64) | GRIA1GRIA2GRIA4GRIK5GRIA3 | |
| SCHEMBL16167009 | 0.69 | MAPT (0.43) | GRIA1GRIA2GRIA4GRIK5GRIA3 | |
| SCHEMBL5846928 | 0.67 | HPGD (0.60) | GRIA1GRIA2GRIA4GRIK5MAPT | |
| SCHEMBL10456669 | 0.66 | GRIA1 (0.53) | GRIA1GRIA2GRIA4GRIK5TSHR | |
| SCHEMBL5846757 | 0.65 | HPN (0.49) | MAPTLMNATSHRKDM4ERAB9A | |
| SCHEMBL23211205 | 0.65 | KMT2A (0.59) | GRIA1GRIA2GRIA4GRIK5GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708336-B2 | Anodic oxidation of 5-aminouracil | MEDIBEACON INC. (US) | 2023-07-25 | — | — | US | disclosed |
| CN-114555087-A | Anodic oxidation of 5-aminouracils | 麦迪贝肯有限公司 | 2022-05-27 | — | — | CN | disclosed |
| US-20220002254-A9 | ANODIC OXIDATION OF 5-AMINOURACIL | MEDIBEACON INC. | 2022-01-06 | — | — | US | disclosed |
| WO-2021072159-A1 | ANODIC OXIDATION OF 5-AMINOURACIL | MEDIBEACON INC. (US) | 2021-04-15 | — | — | WO | disclosed |
| US-20210107881-A1 | ANODIC OXIDATION OF 5-AMINOURACIL | MEDIBEACON INC (US) | 2021-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708336-B2 | Anodic oxidation of 5-aminouracil | DPYD, DHODH, AASDHPPT | GRIA1 1936/4885GRIA2 929/4885GRIA4 1387/4885 |
| US-20220002254-A9 | ANODIC OXIDATION OF 5-AMINOURACIL | DPYD, DHODH, AASDHPPT | GRIA1 1936/4885GRIA2 929/4885GRIA4 1387/4885 |
| US-20210107881-A1 | ANODIC OXIDATION OF 5-AMINOURACIL | DPYD, DHODH, AASDHPPT | GRIA1 1936/4885GRIA2 929/4885GRIA4 1387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.