Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 8/20 | 0.51 |
| ▸ | FAP | Q12884 | 2/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | AKT2 | P31751 | 1/20 | 0.47 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21410996 | 1.00 | S1PR1 (0.51) | S1PR1S1PR5DPP4FAPDPP8 | |
| SCHEMBL22255191 | 0.86 | DPP4 (0.53) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL28499545 | 0.85 | ALDH1A1 (0.50) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL29910014 | 0.85 | ALDH1A1 (0.50) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL23211434 | 0.82 | DPP4 (0.50) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL23211432 | 0.82 | DPP4 (0.50) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL23211353 | 0.81 | DPP7 (0.56) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL23211354 | 0.81 | DPP7 (0.56) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL21411220 | 0.81 | DPP4 (0.61) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL23211381 | 0.81 | DPP4 (0.61) | DPP4FAPDPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240174685-A1 | OX2R Compounds | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-05-30 | — | — | US | disclosed |
| US-11905297-B2 | OX2R compounds | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-02-20 | — | — | US | disclosed |
| US-20230122024-A1 | OX2R Compounds | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-04-20 | — | — | US | disclosed |
| US-20210163494-A1 | OX2R Compounds | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-06-03 | — | — | US | disclosed |
| US-20210107914-A1 | OX2R Compounds | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11905297-B2 | OX2R compounds | HCRTR2, HCRTR1, OXTR | S1PR1 439/4885S1PR5 504/4885DPP4 4445/4885 |
| US-20240174685-A1 | OX2R Compounds | HCRTR2, HCRTR1, OXTR | S1PR1 439/4885S1PR5 504/4885DPP4 4445/4885 |
| US-20210107914-A1 | OX2R Compounds | HCRTR2, HCRTR1, OXTR | S1PR1 439/4885S1PR5 504/4885DPP4 4445/4885 |
| US-20230122024-A1 | OX2R Compounds | HCRTR2, HCRTR1, OXTR | S1PR1 439/4885S1PR5 504/4885DPP4 4445/4885 |
| US-20210163494-A1 | OX2R Compounds | HCRTR2, HCRTR1, OXTR | S1PR1 439/4885S1PR5 504/4885DPP4 4445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.