SCHEMBL2321164

SCHEMBL2321164

CC(N)c1cc(-c2ncnc(Nc3cccc(Cl)c3)n2)ccn1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 6/20 0.57
KDR P35968 4/20 0.57
CDK2 P24941 4/20 0.57
CDK4 P11802 3/20 0.57
CDK5 Q00535 3/20 0.57
CDK5R1 Q15078 3/20 0.57
CCNB1 P14635 2/20 0.57
CCNA2 P20248 2/20 0.57
CCND1 P24385 2/20 0.57
CDK7 P50613 2/20 0.57
CCNH P51946 2/20 0.57
CCNB2 O95067 1/20 0.57
CCND3 P30281 1/20 0.57
CSNK1A1 P48729 1/20 0.57
CSNK1D P48730 1/20 0.57
CSNK1E P49674 1/20 0.57
CSNK1G2 P78368 1/20 0.57
CCNA1 P78396 1/20 0.57
CDK6 Q00534 1/20 0.57
CCNB3 Q8WWL7 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2322755 0.84 CAMK2D (0.66) CDK1CDK2CDK4CDK5CDK5R1
Ammonia Solution, Strong SCHEMBL2323892 0.83 CAMK2D (0.65) CDK1CDK2CDK4CDK5CDK5R1
SCHEMBL17614050 0.83 CDK1 (0.62) CDK1KDRCDK2CDK4CDK5
SCHEMBL2321693 0.83 CDK1 (0.65) CDK1KDRCDK2CDK4CDK5
SCHEMBL2330734 0.80 CDK1 (0.62) CDK1KDRCDK2CDK4CDK5
SCHEMBL2325948 0.80 CAMK2D (0.62) CDK1KDRCDK2CDK4CDK5
SCHEMBL2329924 0.80 CDK1 (0.61) CDK1KDRCDK2CDK4CDK5
SCHEMBL2333459 0.79 KDR (0.61) CDK1KDRCDK2CDK4CDK5
SCHEMBL2324901 0.79 CDK1 (0.61) CDK1KDRCDK2CDK4CDK5
SCHEMBL6475594 0.78 CDK1 (0.66) CDK1KDRCDK2CDK4CDK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110294810-A1 SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS BAYER CROPSCIENCE AG (DE) 2011-12-01 US disclosed
CN-102216286-A Substituted (pyridyl)-azinylamine derivatives as plant protection agents BAYER CROPSCIENCE SA 2011-10-12 CN disclosed
EP-2356102-A1 SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS Bayer CropScience AG (DE) 2011-08-17 EP disclosed
WO-2010055114-A1 SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS BAYER CROPSCIENCE SA (FR) 2010-05-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294810-A1 SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS PRXL2A, AZI2, PIR CDK1 536/4885KDR 4222/4885CDK2 1282/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.