Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HINT1 | P49773 | 2/20 | 0.48 |
| ▸ | POLA1 | P09884 | 1/20 | 0.46 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.45 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.45 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.45 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.45 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | PNP | P00491 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017969 | 0.91 | KDM4E (0.51) | KDM4EPOLBHPGDHINT1POLA1 | |
| SCHEMBL18769456 | 0.91 | POLB (0.54) | KDM4EPOLBHINT1P2RY2P2RY4 | |
| SCHEMBL17001491 | 0.91 | POLB (0.54) | KDM4EPOLBHINT1P2RY2P2RY4 | |
| SCHEMBL23352540 | 0.91 | POLB (0.54) | KDM4EPOLBHINT1P2RY2P2RY4 | |
| SCHEMBL3893075 | 0.91 | POLB (0.54) | KDM4EPOLBHINT1P2RY2P2RY4 | |
| SCHEMBL2775081 | 0.91 | POLB (0.54) | KDM4EPOLBHINT1P2RY2P2RY4 | |
| SCHEMBL31098063 | 0.90 | KDM4E (0.58) | KDM4EPOLBHPGDHINT1POLA1 | |
| SCHEMBL3279870 | 0.89 | POLB (0.56) | KDM4EPOLBHPGDHINT1POLA1 | |
| SCHEMBL16359975 | 0.89 | POLB (0.56) | KDM4EPOLBHPGDHINT1POLA1 | |
| SCHEMBL3279868 | 0.89 | POLB (0.56) | KDM4EPOLBHPGDHINT1POLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161869-B2 | Thermally-cleavable protecting and linker groups | EVONETIX LTD. (GB) | 2021-11-02 | — | — | US | disclosed |
| US-20210107934-A1 | THERMALLY-CLEAVABLE PROTECTING AND LINKER GROUPS | SILICON VALLEY BANK | 2021-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210107934-A1 | THERMALLY-CLEAVABLE PROTECTING AND LINKER GROUPS | CTDSP1, RNGTT, SSU72 | KDM4E 2740/4885POLB 24/4885HPGD 1514/4885 |
| US-11161869-B2 | Thermally-cleavable protecting and linker groups | CTDSP1, RNGTT, SSU72 | KDM4E 2740/4885POLB 24/4885HPGD 1514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.