SCHEMBL23211971

SCHEMBL23211971

C[Si](C)(C1C=Cc2ccccc21)C1C=Cc2cc3c(cc21)CCC3

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL60904 0.81 HTR2A (0.38) LMNA
SCHEMBL29843993 0.81 HTR2A (0.38) LMNA
SCHEMBL20996206 0.81
SCHEMBL30084517 0.81
SCHEMBL30084466 0.81
SCHEMBL20996198 0.81
SCHEMBL20996255 0.80
Lithium SCHEMBL30084463 0.80
Lithium SCHEMBL9141948 0.79 HTR2A (0.36) LMNA
SCHEMBL9143696 0.79 HTR2A (0.36) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11472828-B2 Indacene based metallocene catalysts useful in the production of propylene polymers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-10-18 US disclosed
US-20210107930-A1 Indacene Based Metallocene Catalysts Useful in the Production of Propylene Polymers EXXONMOBIL CHEMICAL PATENTS INC. 2021-04-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11472828-B2 Indacene based metallocene catalysts useful in the production of propylene polymers INF2, INTS6, PORCN NPC1 4368/4885LMNA 3567/4885
US-20210107930-A1 Indacene Based Metallocene Catalysts Useful in the Production of Propylene Polymers INF2, INTS6, PORCN NPC1 4368/4885LMNA 3567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.