SCHEMBL60904

SCHEMBL60904

C[Si](C)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.38
HTR6 P50406 1/20 0.37
KDM4E B2RXH2 2/20 0.34
CYP2D6 P10635 2/20 0.34
BRD4 O60885 1/20 0.34
CCL2 P13500 1/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
CHRM2 P08172 1/20 0.34
CYP3A4 P08684 1/20 0.34
CHRM1 P11229 1/20 0.34
DRD2 P14416 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
NFKB1 P19838 1/20 0.34
CHRM3 P20309 1/20 0.34
SLC6A2 P23975 1/20 0.34
HTR2C P28335 1/20 0.34
ADRA1A P35348 1/20 0.34
HRH1 P35367 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29843993 1.00 HTR2A (0.38) HTR2AHTR6KDM4ECYP2D6BRD4
SCHEMBL9141944 0.98 HTR2A (0.36) HTR2AHTR6KDM4ECYP2D6BRD4
SCHEMBL9143696 0.98 HTR2A (0.36) HTR2AHTR6KDM4ECYP2D6BRD4
Lithium SCHEMBL9141948 0.98 HTR2A (0.36) HTR2AHTR6KDM4ECYP2D6BRD4
SCHEMBL9143717 0.98 HTR2A (0.36) HTR2AHTR6KDM4ECYP2D6BRD4
Hydrochloric Acid SCHEMBL6771310 0.96 HTR2A (0.35) HTR2AHTR6KDM4ECYP2D6BRD4
Hydrochloric Acid SCHEMBL3627746 0.96 HTR2A (0.35) HTR2AHTR6KDM4ECYP2D6BRD4
Hydrochloric Acid SCHEMBL3627842 0.96 HTR2A (0.35) HTR2AHTR6KDM4ECYP2D6BRD4
Hydrochloric Acid SCHEMBL6772747 0.96 HTR2A (0.35) HTR2AHTR6KDM4ECYP2D6BRD4
SCHEMBL1028330 0.89 HTR2A (0.39) HTR2AHTR6KDM4ECYP2D6BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 418 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109456439-B Photoinitiated rapidly-prepared polymethacrylimide foamable particle 浙江中科恒泰新材料科技有限公司 2021-07-27 CN claimed
US-8038972-B2 Higher order silane composition, method for manufacturing film-coated substrate, electro-optical device and electronic device SEIKO EPSON CORPORATION (JP) 2011-10-18 US claimed
EP-1003756-B1 PRODUCTION OF BRIDGED HAFNOCENES ALBEMARLE CORP (US) 2002-11-20 EP claimed
US-6444605-B1 REACTING A REACTION PRODUCT OF A MAGNESIUM ALKOXIDE OR ARYLOXIDE AND A GROUP IVB METAL ALKOXIDE OR ARYLOXIDE; AND A CYCLIC OR POLYCYCLIC HYDROCARBON; PREPARING POLYOLEFINS WITH BROAD OR BIMODAL MOLECULAR WEIGHT DISTRIBUTION UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION 2002-09-03 US claimed
US-6399531-B1 COORDINATION CATALYST UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION 2002-06-04 US claimed
US-20010039349-A1 Selective, Catalytic, thermal functionalization of secondary or aromatic C-H cyclic hydrocarbon bonds SHELL OIL COMPANY 2001-11-08 US claimed
US-6232256-B1 CONTACTING A CYCLOALKADIENYL COMPOUND, A TRANSITION METAL AMIDE, AN ALUMINOXANE, AND OPTIONALLY A SOLID SUPPORT UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION 2001-05-15 US claimed
EP-0933383-A1 Catalyst composition for the polymerization of olefins UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-08-04 EP claimed
US-12590174-B2 Curable compositions comprising telechelic polyolefins DOW GLOBAL TECHNOLOGIES LLC (US) 2026-03-31 US disclosed
EP-3902808-B1 CURABLE COMPOSITIONS COMPRISING UNSATURATED POLYOLEFINS DOW GLOBAL TECHNOLOGIES LLC (US) 2026-01-14 EP disclosed
EP-3902810-B1 CURABLE COMPOSITIONS COMPRISING TELECHELIC POLYOLEFINS DOW GLOBAL TECHNOLOGIES LLC (US) 2026-01-14 EP disclosed
EP-3356374-B1 MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2025-09-24 EP disclosed
EP-3902807-B1 ORGANOMETALLIC CHAIN TRANSFER AGENTS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-07-09 EP disclosed
US-12351707-B2 Curable compositions comprising unsaturated polyolefins DOW GLOBAL TECHNOLOGIES LLC (US) 2025-07-08 US disclosed
EP-0538749-A1 Propylene copolymer composition MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1993-04-28 EP disclosed
EP-0520811-A2 Catalyst components for polymerization of olefins NIPPON OIL CO. LTD. (JP) 1992-12-30 EP disclosed
EP-0520816-A2 Catalyst components for polymerization of olefins NIPPON OIL CO. LTD. (JP) 1992-12-30 EP disclosed
EP-0512741-A1 Process for producing a propylene random copolymer MITSUBISHI CHEMICAL CORPORATION (JP) 1992-11-11 EP disclosed
EP-0504418-A1 PROCESS FOR PRODUCING CYCLOOLEFIN POLYMER, CYCLOOLEFIN COPOLYMER, AND COMPOSITION AND MOLDING PREPARED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-23 EP disclosed
EP-0498675-A2 Production of alpha-olefin polymers MITSUBISHI CHEMICAL CORPORATION (JP) 1992-08-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590174-B2 Curable compositions comprising telechelic polyolefins CCT2, TCP1, ECH1 HTR2A 3036/4885HTR6 3284/4885KDM4E 1055/4885
US-12351707-B2 Curable compositions comprising unsaturated polyolefins ACSL6, ELOVL6, ALOX5 HTR2A 3758/4885HTR6 1536/4885KDM4E 2783/4885
US-20010039349-A1 Selective, Catalytic, thermal functionalization of secondary or aromatic C-H cyclic hydrocarbon bonds AHR, PAH, HRH3 HTR2A 1242/4885HTR6 1154/4885KDM4E 2533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.