SCHEMBL23212331

SCHEMBL23212331

COC(C)Cc1ccc(CC(C)C=O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.58
TP53 P04637 1/20 0.58
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
LDHA P00338 1/20 0.38
SLC6A4 P31645 1/20 0.36
CTSK P43235 2/20 0.35
CTSL P07711 1/20 0.35
CTSB P07858 1/20 0.35
CTSH P09668 1/20 0.35
CYP26A1 O43174 1/20 0.34
PTGS1 P23219 3/20 0.34
PTGS2 P35354 3/20 0.34
LMNA P02545 2/20 0.34
CYP2C9 P11712 2/20 0.34
AKR1C3 P42330 2/20 0.34
CXCR1 P25024 2/20 0.34
CXCR2 P25025 2/20 0.34
ALB P02768 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43314 0.83 SLC6A4 (0.46) TAAR1LDHASLC6A4
SCHEMBL10433291 0.82 ALDH1A3 (0.47) TSHRTP53MEN1KMT2ATAAR1
SCHEMBL2399751 0.81 TSHR (0.54) TSHRTP53PTGS1PTGS2LMNA
SCHEMBL30290019 0.81 SLC6A4 (0.58) TSHRTP53LDHASLC6A4
SCHEMBL8283115 0.81 SLC6A4 (0.58) TSHRTP53LDHASLC6A4
SCHEMBL113550 0.81 SLC6A4 (0.58) TSHRTP53LDHASLC6A4
SCHEMBL9900714 0.81 SLC6A4 (0.58) TSHRTP53LDHASLC6A4
SCHEMBL97559 0.79 TP53 (0.60) TSHRTP53MEN1KMT2ATAAR1
SCHEMBL31412811 0.79 TSHR (0.66) TSHRTP53MEN1KMT2APTGS1
SCHEMBL225582 0.79 TSHR (0.66) TSHRTP53MEN1KMT2APTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021069331-A1 LILY OF THE VALLEY ODORANT FIRMENICH SA (CH) 2021-04-15 WO disclosed