SCHEMBL43314

SCHEMBL43314

COC(C)Cc1ccc(CC(C)OC)cc1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 3/20 0.46
LDHA P00338 1/20 0.43
TAAR1 Q96RJ0 6/20 0.42
SLC6A2 P23975 2/20 0.42
SIGMAR1 Q99720 2/20 0.42
MAOA P21397 1/20 0.42
SLC6A3 Q01959 1/20 0.42
CYP2A6 P11509 1/20 0.42
ADORA2A P29274 1/20 0.42
ADORA1 P30542 1/20 0.42
SLC18A2 Q05940 1/20 0.39
CYP2D6 P10635 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6551869 0.91 AGXT (0.41) SLC6A4LDHATAAR1CYP2A6
SCHEMBL2555409 0.90 SIGMAR1 (0.56) SLC6A4TAAR1SLC6A2SIGMAR1MAOA
SCHEMBL13189946 0.90 SIGMAR1 (0.56) SLC6A4TAAR1SLC6A2SIGMAR1MAOA
SCHEMBL13006663 0.90 SIGMAR1 (0.56) SLC6A4TAAR1SLC6A2SIGMAR1MAOA
SCHEMBL9694562 0.89 TRPA1 (0.42) SLC6A4LDHATAAR1SLC6A2SIGMAR1
SCHEMBL12665322 0.89 SLC6A4 (0.44) SLC6A4TAAR1SLC6A2SIGMAR1MAOA
SCHEMBL14706798 0.89 TSHR (0.42) SLC6A4LDHATAAR1SLC6A2
SCHEMBL1840026 0.89 TAAR1 (0.57) TAAR1SLC6A2SIGMAR1
SCHEMBL10433291 0.85 ALDH1A3 (0.47) SLC6A4LDHATAAR1CYP2A6
SCHEMBL5958332 0.84 TAAR1 (0.35) SLC6A4LDHATAAR1SLC6A2SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2284203-B1 Method for preparation of polyolefins containing exo-olefin chain ends CHEVRON ORONITE CO (US) 2015-03-04 EP claimed
US-8575279-B2 Method for preparation of polyolefins containing exo-olefin chain ends CHEVRON ORONITE COMPANY LLC (US) 2013-11-05 US claimed
US-20130150539-A1 METHOD FOR PREPARATION OF POLYOLEFINS CONTAINING EXO-OLEFIN CHAIN ENDS THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2013-06-13 US claimed
US-8383736-B2 Method for preparation of polyolefins containing exo-olefin chain ends CHEVRON ORONITE COMPANY LLC (US) 2013-02-26 US claimed
US-8063154-B2 Preparation of exo-olefin terminated polyolefins via quenching with alkoxysilanes or ethers THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2011-11-22 US claimed
US-8013073-B2 Method for preparing polyolefins containing vinylidine end groups using nonaromatic heterocyclic compounds CHEVRON ORONITE COMPANY LLC (US) 2011-09-06 US claimed
EP-1781715-B1 METHOD FOR PREPARATION OF POLYOLEFINS CONTAINING EXO-OLEFIN CHAIN ENDS CHEVRON ORONITE CO (US) 2011-05-18 EP claimed
EP-2284203-A2 Method for preparation of polyolefins containing exo-olefin chain ends Chevron Oronite Company LLC (US) 2011-02-16 EP claimed
EP-2279214-A1 PRODUCTION OF VINYLIDENE-TERMINATED POLYOLEFINS VIA QUENCHING WITH MONOSULFIDES Chevron Oronite Company LLC (US) 2011-02-02 EP claimed
US-20100311915-A1 METHOD FOR PREPARATION OF POLYOLEFINS CONTAINING EXO-OLEFIN CHAIN ENDS CHEVRON ORONITE COMPANY LLC 2010-12-09 US claimed
EP-0609737-B1 Process for producing a halogenated butyl rubber BAYER INC (CA) 2000-06-07 EP claimed
US-5473029-A Copolymerization of isobutylene with a conjugated diolefin bearing an allylic halide in the presence of an initiator and a lewis acid BAYER RUBBER INC. (CA) 1995-12-05 US claimed
US-5399646-A Alkylidenenorbornene polymer and process for producing the same NIPPON ZEON CO., LTD. (JP) 1995-03-21 US claimed
EP-0609737-A2 Process for producing a halogenated butyl rubber BAYER RUBBER INC. (CA) 1994-08-10 EP claimed
US-RE34640-E Polymerizing isobutylene, adding monomer to make block polymer; metal halide, initiator and electron pair doner solvent UNIVERSITY OF AKRON (US) 1994-06-14 US claimed
EP-0341012-B1 UNIFORM MOLECULAR WEIGHT POLYMERS EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) 1992-12-30 EP claimed
WO-1991011468-A1 NEW THERMOPLASTIC ELASTOMERS THE UNIVERSITY OF AKRON (US) 1991-08-08 WO claimed
US-4946899-A CARBOCATIONIC POLYMERIZATION INVOLVING HOMOPOLYMERIZATION OF ELASTOMER FOLLOWED BY COPOLYMERIZATION TO ADD GLASSY SEGMENTS; FORMING LIVING POLYMERS WITH A METAL HALIDE, PROMOTER AND SOLVENT MIXTURE THE UNIVERSITY OF AKRON (US) 1990-08-07 US claimed
EP-0346919-A2 Improved thermoplastic elastomers EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) 1989-12-20 EP claimed
EP-0341012-A2 Uniform molecular weight polymers EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) 1989-11-08 EP claimed