Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4192158 | 0.98 | KLKB1 (0.48) | KLKB1PKMENPP2PIK3CDPIK3CA | |
| SCHEMBL23623150 | 0.96 | KLKB1 (0.44) | KLKB1PKMENPP2PIK3CDPIK3CA | |
| SCHEMBL3259744 | 0.92 | PIK3CD (0.46) | KLKB1PKMENPP2PIK3CDPIK3CA | |
| Hydrochloric Acid SCHEMBL17003092 | 0.91 | MAPT (0.45) | KLKB1PKMENPP2PIK3CDPIK3CA | |
| Cyanide SCHEMBL27964377 | 0.87 | PIK3CD (0.43) | KLKB1PKMENPP2PIK3CDPIK3CA | |
| SCHEMBL16593759 | 0.84 | LRRK2 (0.41) | KLKB1PKMPIK3CDPIK3CAPIK3CB | |
| SCHEMBL1703769 | 0.83 | HDAC1 (0.47) | KLKB1PKMENPP2PIK3CDPIK3CA | |
| SCHEMBL1665196 | 0.82 | KLKB1 (0.41) | KLKB1ENPP2LMNAHDAC1HDAC2 | |
| SCHEMBL31361594 | 0.82 | KLKB1 (0.41) | KLKB1ENPP2LMNAHDAC1HDAC2 | |
| SCHEMBL31361733 | 0.82 | KLKB1 (0.41) | KLKB1ENPP2LMNAHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119751439-A | ATF6 modulators and uses thereof | 阿尔托斯实验室公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-115087656-B | ATF6 modulators and uses thereof | 阿尔托斯实验室公司 | 2024-12-13 | — | — | CN | disclosed |
| US-20230028584-A1 | ATF6 MODULATORS AND USES THEREOF | ALTOS LABS, INC. | 2023-01-26 | — | — | US | disclosed |
| US-20230028584-A1 | ATF6 MODULATORS AND USES THEREOF | ALTOS LABS, INC. | 2023-01-26 | — | — | US | disclosed |
| CN-115087656-A | ATF6 modulators and uses thereof | 普拉西斯生物技术有限责任公司 | 2022-09-20 | — | — | CN | disclosed |
| EP-4041728-A1 | ATF6 MODULATORS AND USES THEREOF | Praxis Biotech LLC (US) | 2022-08-17 | — | — | EP | disclosed |
| WO-2021069721-A1 | ATF6 MODULATORS AND USES THEREOF | BLACK BELT TX LTD (GB) | 2021-04-15 | — | — | WO | disclosed |
| WO-2021069721-A1 | ATF6 MODULATORS AND USES THEREOF | BLACK BELT TX LTD (GB) | 2021-04-15 | — | — | WO | disclosed |
| CN-108026101-A | fused pyrimidine compound or salt thereof | 大鹏药品工业株式会社 | 2018-05-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230028584-A1 | ATF6 MODULATORS AND USES THEREOF | ATF4, XBP1, ATF1 | KLKB1 4270/4885PKM 2540/4885ENPP2 964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.