Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665196 | 1.00 | KLKB1 (0.41) | KLKB1CHRM2ADRA2ACHRM1DRD1 | |
| SCHEMBL31361594 | 1.00 | KLKB1 (0.41) | KLKB1CHRM2ADRA2ACHRM1DRD1 | |
| SCHEMBL1703769 | 0.83 | HDAC1 (0.47) | KLKB1HRH3CHRM3TLR7HDAC1 | |
| SCHEMBL23212539 | 0.82 | KLKB1 (0.46) | KLKB1HDAC1HDAC2LMNAENPP2 | |
| SCHEMBL23623150 | 0.82 | KLKB1 (0.44) | KLKB1HDAC1HDAC2LMNAENPP2 | |
| SCHEMBL4192158 | 0.81 | KLKB1 (0.48) | KLKB1HDAC1HDAC2LMNAENPP2 | |
| SCHEMBL3259744 | 0.79 | PIK3CD (0.46) | KLKB1HDAC1HDAC2LMNAENPP2 | |
| SCHEMBL22774916 | 0.78 | CHRNB2 (0.40) | HTR6 | |
| Hydrochloric Acid SCHEMBL17003092 | 0.77 | MAPT (0.45) | KLKB1HDAC1HDAC2LMNAENPP2 | |
| SCHEMBL27869422 | 0.76 | KLKB1 (0.38) | KLKB1HDAC1HDAC2LMNAENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025017116-A1 | PHARMACEUTICAL COMPOUNDS HAVING ACTIVITY AS WEE1 INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2025-01-23 | — | — | WO | disclosed |