Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F12 | P00748 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29751647 | 1.00 | CHRNA7 (0.45) | CHRNA7CTSDIDO1PDE7APDE7B | |
| Hydrochloric Acid SCHEMBL23212660 | 0.99 | IDO1 (0.44) | CHRNA7CTSDIDO1PDE7APDE7B | |
| Hydrochloric Acid SCHEMBL29751753 | 0.99 | IDO1 (0.44) | CHRNA7CTSDIDO1PDE7APDE7B | |
| SCHEMBL22619811 | 0.91 | HTR6 (0.41) | CHRNA7CTSDIDO1HSD11B1HTR6 | |
| SCHEMBL30839410 | 0.91 | HTR6 (0.41) | CHRNA7CTSDIDO1HSD11B1HTR6 | |
| Hydrochloric Acid SCHEMBL22619807 | 0.90 | IDO1 (0.41) | CHRNA7CTSDIDO1HTR6 | |
| Hydrochloric Acid SCHEMBL22619864 | 0.90 | IDO1 (0.41) | CHRNA7CTSDIDO1HTR6 | |
| Hydrochloric Acid SCHEMBL31039804 | 0.90 | IDO1 (0.41) | CHRNA7CTSDIDO1HTR6 | |
| SCHEMBL23212694 | 0.77 | MEN1 (0.46) | CHRNA7PDE7APDE7BHSD11B1F2 | |
| SCHEMBL29751635 | 0.77 | MEN1 (0.46) | CHRNA7PDE7APDE7BHSD11B1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041727-B1 | ATF6 MODULATORS AND USES THEREOF | ALTOS LABS INC (US) | 2026-05-20 | — | — | EP | disclosed |
| US-20220389001-A1 | ATF6 MODULATORS AND USES THEREOF | ALTOS LABS, INC. | 2022-12-08 | — | — | US | disclosed |
| US-20220389001-A1 | ATF6 MODULATORS AND USES THEREOF | ALTOS LABS, INC. | 2022-12-08 | — | — | US | disclosed |
| CN-115135645-A | ATF6 modulators and uses thereof | 普拉西斯生物技术有限责任公司 | 2022-09-30 | — | — | CN | disclosed |
| EP-4041727-A1 | ATF6 MODULATORS AND USES THEREOF | Praxis Biotech LLC (US) | 2022-08-17 | — | — | EP | disclosed |
| WO-2021069701-A1 | ATF6 MODULATORS AND USES THEREOF | BLACK BELT TX LTD (GB) | 2021-04-15 | — | — | WO | disclosed |
| WO-2021069701-A1 | ATF6 MODULATORS AND USES THEREOF | BLACK BELT TX LTD (GB) | 2021-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220389001-A1 | ATF6 MODULATORS AND USES THEREOF | ATF4, XBP1, ATF1 | CHRNA7 4340/4885CTSD 2435/4885IDO1 4770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.