SCHEMBL23212932

SCHEMBL23212932

COC(=O)C(=O)c1cc2ccccc2oc1=O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.73
ALDH1A1 P00352 4/20 0.73
HPGD P15428 1/20 0.73
MAOB P27338 9/20 0.65
CA12 O43570 2/20 0.65
CA9 Q16790 2/20 0.65
CYP1A2 P05177 2/20 0.65
NT5E P21589 1/20 0.65
MAOA P21397 4/20 0.63
CA1 P00915 1/20 0.62
CA3 P07451 1/20 0.62
TSHR P16473 1/20 0.62
CA4 P22748 1/20 0.62
CA6 P23280 1/20 0.62
CA5A P35218 1/20 0.62
CA7 P43166 1/20 0.62
GPR35 Q9HC97 1/20 0.62
CA14 Q9ULX7 1/20 0.62
CA5B Q9Y2D0 1/20 0.62
ATM Q13315 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29851452 1.00 KDM4E (0.73) KDM4EALDH1A1HPGDMAOBCA12
SCHEMBL34468463 0.85 MAOB (0.77) KDM4EALDH1A1HPGDMAOBCA12
SCHEMBL76086 0.84 KDM4E (1.00) KDM4EALDH1A1HPGDMAOBCA12
SCHEMBL23212931 0.82 MAOB (0.69) KDM4EALDH1A1HPGDMAOBCYP1A2
SCHEMBL29851487 0.82 MAOB (0.69) KDM4EALDH1A1HPGDMAOBCYP1A2
SCHEMBL29194146 0.81 MAOB (0.75) KDM4EALDH1A1HPGDMAOBCA12
SCHEMBL7637918 0.80 FLT3 (0.61) KDM4EALDH1A1HPGDTSHRMEN1
3-Acetylcoumarin SCHEMBL31097378 0.79 MAOB (1.00) KDM4EALDH1A1HPGDMAOBCA12
3-Acetylcoumarin SCHEMBL181862 0.79 MAOB (1.00) KDM4EALDH1A1HPGDMAOBCA12
SCHEMBL279860 0.79 MAOB (0.77) KDM4EALDH1A1HPGDMAOBCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11981650-B2 Coumarin glyoxylates for LED photocuring IGM RESINS ITALIA S.R.L. (IT) 2024-05-14 US disclosed
US-20240067620-A1 COUMARIN GLYOXYLATES FOR LED PHOTOCURING IGM RESINS ITALIA S.R.L. (IT) 2024-02-29 US disclosed
EP-4041719-A1 COUMARIN GLYOXYLATES FOR LED PHOTOCURING IGM Resins Italia S.r.l. (IT) 2022-08-17 EP disclosed
CN-114829348-A Coumarin glyoxylate for LED photocuring 意大利艾坚蒙树脂有限公司 2022-07-29 CN disclosed
WO-2021070152-A1 COUMARIN GLYOXYLATES FOR LED PHOTOCURING IGM RESINS ITALIA S.R.L. (IT) 2021-04-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240067620-A1 COUMARIN GLYOXYLATES FOR LED PHOTOCURING AGXT, GRHPR, GLO1 KDM4E 2572/4885ALDH1A1 1173/4885HPGD 561/4885
US-11981650-B2 Coumarin glyoxylates for LED photocuring AGXT, GRHPR, GLO1 KDM4E 2572/4885ALDH1A1 1173/4885HPGD 561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.