Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 6/20 | 0.70 |
| ▸ | TYMS | P04818 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20699855 | 0.93 | FDPS (0.75) | FDPSTYMS | |
| SCHEMBL10863085 | 0.90 | FDPS (0.76) | FDPS | |
| SCHEMBL10785210 | 0.86 | FDPS (0.67) | FDPSTYMSKDM4EMMP2THRB | |
| SCHEMBL5003869 | 0.85 | FDPS (0.61) | FDPSTYMSALDH1A1TDP1 | |
| SCHEMBL2322124 | 0.85 | FDPS (0.61) | FDPSTYMSALDH1A1TDP1 | |
| SCHEMBL1815322 | 0.85 | FDPS (0.61) | FDPSALDH1A1 | |
| SCHEMBL3854503 | 0.85 | FDPS (0.61) | FDPSTYMSALDH1A1TDP1 | |
| SCHEMBL8983328 | 0.84 | FDPS (0.54) | FDPSALDH1A1TDP1 | |
| SCHEMBL5011539 | 0.83 | FDPS (0.62) | FDPS | |
| SCHEMBL5011508 | 0.83 | FDPS (0.58) | FDPSTYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3413934-B1 | IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS | NANO BRIDGING MOLECULES SA (CH) | 2021-10-13 | — | — | EP | claimed |
| CN-109195641-B | Improved implant treatment with phosphonic acid compounds | 纳米桥接分子股份公司 | 2021-07-27 | — | — | CN | claimed |
| US-11000627-B2 | Treatment of implants with phosphonic acid compounds | NANO BRIDGING MOLECULES SA (CH) | 2021-05-11 | — | — | US | claimed |
| EP-1698357-B1 | POLYPHOSPHONIC ACIDS AND DERIVATIVES THEREOF | UNIV GENEVE (CH) | 2019-06-26 | — | — | EP | claimed |
| US-20190038802-A1 | IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS | NANO BRIDGING MOLECULES SA (CH) | 2019-02-07 | — | — | US | claimed |
| EP-3413934-A1 | IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS | Nano Bridging Molecules SA (CH) | 2018-12-19 | — | — | EP | claimed |
| WO-2017137623-A1 | IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS | NANO BRIDGING MOLECULES SA (CH) | 2017-08-17 | — | — | WO | claimed |
| US-9730795-B2 | Endosseous implant | UNIVERSITE DE GENEVE (CH) | 2017-08-15 | — | — | US | claimed |
| EP-1351722-B2 | ENDOSSEOUS IMPLANT | UNIV GENEVE (CH) | 2016-02-17 | — | — | EP | claimed |
| US-20140316533-A1 | ENDOSSEOUS IMPLANT | UNIV GENEVE (CH) | 2014-10-23 | — | — | US | claimed |
| US-7090496-B2 | Endosseous implant | UNIVERSITE DE GENEVE (CH) | 2006-08-15 | — | — | US | claimed |
| EP-1351722-B1 | ENDOSSEOUS IMPLANT | UNIV GENEVE (CH) | 2006-07-05 | — | — | EP | claimed |
| EP-1343545-B1 | ENDOSSEOUS IMPLANT | UNIV GENEVE (CH) | 2006-07-05 | — | — | EP | claimed |
| US-20040054422-A1 | Endosseous implant | UNIVERSITE DE GENEVE (CH) | 2004-03-18 | — | — | US | claimed |
| US-20040049287-A1 | Surface treated with a phosphonic acid, ester, amide or salt; orthopaedic prostheses; bone replacements or reinforcements, dentistry | UNIVERSITE DE GENEVE (CH) | 2004-03-11 | — | — | US | claimed |
| EP-1351722-A1 | ENDOSSEOUS IMPLANT | UNIVERSITE DE GENEVE (CH) | 2003-10-15 | — | — | EP | claimed |
| EP-1343545-A1 | ENDOSSEOUS IMPLANT | UNIVERSITE DE GENEVE (CH) | 2003-09-17 | — | — | EP | claimed |
| WO-2002040074-A1 | ENDOSSEOUS IMPLANT | UNIVERSITE DE GENEVE (CH) | 2002-05-23 | — | — | WO | claimed |
| WO-2002040073-A1 | ENDOSSEOUS IMPLANT | UNIVERSITÉ DE GENÈVE (CH) | 2002-05-23 | — | — | WO | claimed |
| WO-2002040075-A1 | ENDOSSEOUS IMPLANT | UNIVERSITÉ DE GENÈVE (CH) | 2002-05-23 | — | — | WO | claimed |