SCHEMBL2322124

SCHEMBL2322124

O=P(O)(O)CCCC(P(=O)(O)O)P(=O)(O)O

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FDPS P14324 6/20 0.61
TYMS P04818 1/20 0.58
ALDH1A1 P00352 2/20 0.56
TDP1 Q9NUW8 1/20 0.56
ENPEP Q07075 1/20 0.52
LMNA P02545 1/20 0.48
CYP3A4 P08684 1/20 0.48
NFKB1 P19838 1/20 0.48
BLM P54132 1/20 0.48
PMP22 Q01453 1/20 0.48
LPAR3 Q9UBY5 3/20 0.44
LPAR2 Q9HBW0 1/20 0.44
BBOX1 O75936 1/20 0.42
BHMT Q93088 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2322092 0.92 FDPS (0.62) FDPSTYMSALDH1A1TDP1ENPEP
SCHEMBL19212013 0.90 FDPS (0.64) FDPSTYMSALDH1A1TDP1LMNA
SCHEMBL5720518 0.90 FDPS (0.60) FDPSTYMSALDH1A1TDP1ENPEP
SCHEMBL2321372 0.85 FDPS (0.70) FDPSTYMSALDH1A1TDP1
SCHEMBL20699855 0.85 FDPS (0.75) FDPSTYMS
SCHEMBL5720460 0.82 FDPS (0.57) FDPSTYMSALDH1A1TDP1ENPEP
SCHEMBL10863085 0.82 FDPS (0.76) FDPS
SCHEMBL241353 0.80 TYMS (0.61) TYMSALDH1A1TDP1ENPEPLMNA
SCHEMBL10785210 0.78 FDPS (0.67) FDPSTYMS
SCHEMBL3854503 0.78 FDPS (0.61) FDPSTYMSALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3413934-B1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS NANO BRIDGING MOLECULES SA (CH) 2021-10-13 EP claimed
CN-109195641-B Improved implant treatment with phosphonic acid compounds 纳米桥接分子股份公司 2021-07-27 CN claimed
US-11000627-B2 Treatment of implants with phosphonic acid compounds NANO BRIDGING MOLECULES SA (CH) 2021-05-11 US claimed
EP-1698357-B1 POLYPHOSPHONIC ACIDS AND DERIVATIVES THEREOF UNIV GENEVE (CH) 2019-06-26 EP claimed
US-20190038802-A1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS NANO BRIDGING MOLECULES SA (CH) 2019-02-07 US claimed
US-9730795-B2 Endosseous implant UNIVERSITE DE GENEVE (CH) 2017-08-15 US claimed
EP-1351722-B2 ENDOSSEOUS IMPLANT UNIV GENEVE (CH) 2016-02-17 EP claimed
US-20140316533-A1 ENDOSSEOUS IMPLANT UNIV GENEVE (CH) 2014-10-23 US claimed
US-RE43793-E1 Endosseous implant UNIVERSITE DE GENEVE (CH) 2012-11-06 US claimed
US-20120258148-A1 ENDOSSEOUS IMPLANT DESCOUTS PIERRE (FR) 2012-10-11 US claimed
US-7090496-B2 Endosseous implant UNIVERSITE DE GENEVE (CH) 2006-08-15 US claimed
EP-1343545-B1 ENDOSSEOUS IMPLANT UNIV GENEVE (CH) 2006-07-05 EP claimed
EP-1351722-B1 ENDOSSEOUS IMPLANT UNIV GENEVE (CH) 2006-07-05 EP claimed
US-20040054422-A1 Endosseous implant UNIVERSITE DE GENEVE (CH) 2004-03-18 US claimed
US-20040049287-A1 Surface treated with a phosphonic acid, ester, amide or salt; orthopaedic prostheses; bone replacements or reinforcements, dentistry UNIVERSITE DE GENEVE (CH) 2004-03-11 US claimed
EP-1351722-A1 ENDOSSEOUS IMPLANT UNIVERSITE DE GENEVE (CH) 2003-10-15 EP claimed
EP-1343545-A1 ENDOSSEOUS IMPLANT UNIVERSITE DE GENEVE (CH) 2003-09-17 EP claimed
WO-2002040074-A1 ENDOSSEOUS IMPLANT UNIVERSITE DE GENEVE (CH) 2002-05-23 WO claimed
WO-2002040073-A1 ENDOSSEOUS IMPLANT UNIVERSITÉ DE GENÈVE (CH) 2002-05-23 WO claimed
WO-2002040075-A1 ENDOSSEOUS IMPLANT UNIVERSITÉ DE GENÈVE (CH) 2002-05-23 WO claimed