Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31529671 | 0.83 | NPC1 (0.35) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL20066492 | 0.82 | FFAR1 (0.33) | FFAR1FFAR4 | |
| SCHEMBL31529669 | 0.78 | CCR5 (0.34) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL24940716 | 0.78 | FFAR1 (0.36) | FFAR1FFAR4NPC1HPGDMAPK1 | |
| SCHEMBL28416773 | 0.77 | FFAR1 (0.35) | FFAR1FFAR4 | |
| SCHEMBL19677742 | 0.76 | HDAC1 (0.31) | — | |
| SCHEMBL23212683 | 0.75 | NPC1 (0.37) | FFAR1FFAR4NPC1HPGDMAPK1 | |
| SCHEMBL7526965 | 0.74 | LOX (0.31) | NOS2 | |
| SCHEMBL7080317 | 0.73 | HPGD (0.37) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL31459840 | 0.73 | HSD17B10 (0.40) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502691-B | Fluorinated aromatic compounds | 默克专利股份有限公司 | 2025-02-25 | — | — | CN | disclosed |
| US-11964933-B2 | Fluorinated aromatic compounds | MERCK PATENT GMBH (DE) | 2024-04-23 | — | — | US | disclosed |
| EP-4041846-B1 | FLUORINATED AROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2024-04-17 | — | — | EP | disclosed |
| US-20230025385-A1 | FLUORINATED AROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-01-26 | — | — | US | disclosed |
| EP-4041846-A1 | FLUORINATED AROMATIC COMPOUNDS | Merck Patent GmbH (DE) | 2022-08-17 | — | — | EP | disclosed |
| CN-114502691-A | Fluorinated aromatic compounds | 默克专利股份有限公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2021069535-A1 | FLUORINATED AROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2021-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230025385-A1 | FLUORINATED AROMATIC COMPOUNDS | TRPA1, FOXM1, AFF1 | FFAR1 3189/4885FFAR4 3852/4885NPC1 499/4885 |
| US-11964933-B2 | Fluorinated aromatic compounds | TRPA1, FOXM1, AFF1 | FFAR1 3189/4885FFAR4 3852/4885NPC1 499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.