Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 11/20 | 0.55 |
| ▸ | HINT1 | P49773 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.41 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23217422 | 0.92 | TYMP (0.58) | TYMPP2RY6P2RY14P2RY2 | |
| SCHEMBL23215201 | 0.90 | TYMP (0.46) | TYMPHINT1TP53MAPT | |
| SCHEMBL31227920 | 0.87 | TYMS (0.51) | TYMP | |
| SCHEMBL3069438 | 0.84 | TYMP (0.62) | TYMPP2RY6P2RY14 | |
| SCHEMBL15974161 | 0.84 | TYMP (0.62) | TYMPP2RY6P2RY14 | |
| SCHEMBL3069436 | 0.84 | TYMP (0.62) | TYMPP2RY6P2RY14 | |
| SCHEMBL13714472 | 0.84 | TYMP (0.62) | TYMPP2RY6P2RY14 | |
| SCHEMBL9710318 | 0.84 | TYMP (0.62) | TYMPP2RY6P2RY14 | |
| SCHEMBL13205014 | 0.84 | TYMP (0.62) | TYMPP2RY6P2RY14 | |
| SCHEMBL6246850 | 0.84 | TYMP (0.62) | TYMPP2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |
| EP-4022059-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | Wave Life Sciences Ltd. (SG) | 2022-07-06 | — | — | EP | disclosed |
| CN-114585737-A | Oligonucleotide compositions and methods of use thereof | 波涛生命科学有限公司 | 2022-06-03 | — | — | CN | disclosed |
| WO-2021071858-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2021-04-15 | — | — | WO | disclosed |