SCHEMBL23217422

SCHEMBL23217422

CNC(=O)c1cn([C@@H]2O[C@H](COC(c3ccccc3)(c3ccc(OC)cc3)c3ccc(OC)cc3)[C@@H](O)[C@H]2O)c(=O)[nH]c1=O

nearest known ligand 0.58

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ TYMP P19971 13/20 0.58
▸ P2RY14 Q15391 1/20 0.44
▸ P2RY2 P41231 2/20 0.43
▸ P2RY6 Q15077 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23215178 0.92 TYMP (0.55) TYMPP2RY14P2RY2P2RY6
SCHEMBL23216894 0.89 TYMP (0.48) TYMPP2RY14P2RY2
SCHEMBL3069436 0.87 TYMP (0.62) TYMPP2RY14P2RY6
SCHEMBL13714472 0.87 TYMP (0.62) TYMPP2RY14P2RY6
SCHEMBL6246850 0.87 TYMP (0.62) TYMPP2RY14P2RY6
SCHEMBL15974161 0.87 TYMP (0.62) TYMPP2RY14P2RY6
SCHEMBL3069438 0.87 TYMP (0.62) TYMPP2RY14P2RY6
SCHEMBL9710318 0.87 TYMP (0.62) TYMPP2RY14P2RY6
SCHEMBL13205014 0.87 TYMP (0.62) TYMPP2RY14P2RY6
SCHEMBL8197884 0.86 TYMP (0.62) TYMPP2RY14P2RY2P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230220384-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-07-13 — — US disclosed
EP-4022059-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF Wave Life Sciences Ltd. (SG) 2022-07-06 — — EP disclosed
CN-114585737-A Oligonucleotide compositions and methods of use thereof 波涛生命科学有限公司 2022-06-03 — — CN disclosed
WO-2021071858-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF WAVE LIFE SCIENCES LTD. (SG) 2021-04-15 — — WO disclosed
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