Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2320063 | 0.74 | — | — | |
| SCHEMBL18840406 | 0.72 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL31353046 | 0.71 | MAPK1 (0.41) | ALDH1A1CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL26128425 | 0.71 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TSHRRECQLMEN1 | |
| SCHEMBL865183 | 0.71 | TSHR (0.46) | ALDH1A1CYP3A4TSHRCYP1A2RECQL | |
| SCHEMBL2100657 | 0.69 | TSHR (0.55) | ALDH1A1CYP3A4TSHRCYP1A2RECQL | |
| SCHEMBL2319530 | 0.69 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL29940671 | 0.69 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL26129452 | 0.68 | CYP1A2 (0.42) | ALDH1A1CYP3A4TSHRCYP1A2RECQL | |
| SCHEMBL22689185 | 0.67 | NPC1 (0.52) | ALDH1A1MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011097491-A1 | BENZIMIDAZOLE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-08-11 | — | — | WO | disclosed |