Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 19/20 | 0.70 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.57 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | GRK6 | P43250 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29794656 | 1.00 | NTRK1 (0.70) | NTRK1NTRK3NTRK2CYP1A2CYP2D6 | |
| SCHEMBL3338355 | 1.00 | NTRK1 (0.70) | NTRK1NTRK3NTRK2CYP1A2CYP2D6 | |
| SCHEMBL4076751 | 0.93 | NTRK1 (0.66) | NTRK1NTRK3NTRK2CYP1A2CYP2D6 | |
| SCHEMBL4073828 | 0.89 | NTRK1 (0.63) | NTRK1NTRK3NTRK2CYP1A2CYP2D6 | |
| SCHEMBL4069819 | 0.89 | NTRK1 (0.63) | NTRK1NTRK3NTRK2CYP1A2CYP2D6 | |
| SCHEMBL4068937 | 0.87 | NTRK1 (0.72) | NTRK1NTRK3NTRK2CYP1A2CYP2D6 | |
| SCHEMBL4069073 | 0.86 | NTRK1 (0.72) | NTRK1 | |
| SCHEMBL4149345 | 0.86 | NTRK1 (0.66) | NTRK1 | |
| SCHEMBL4151812 | 0.86 | NTRK1 (0.70) | NTRK1NTRK3NTRK2 | |
| SCHEMBL4070713 | 0.85 | NTRK1 (0.63) | NTRK1GRK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945378-A | Feeder-layer and feeder-layer-free stem cell culture systems for stratified epithelial stem cells and uses related thereto | 休斯敦大学体系 | 2022-08-26 | — | — | CN | disclosed |
| WO-2021072238-A1 | FEEDER-BASED AND FEEDER-FREE STEM CELL CULTURE SYSTEMS FOR STRATIFIED EPITHELIAL STEM CELLS, AND USES RELATED THERETO | UNIVERSITY OF HOUSTON SYSTEM (US) | 2021-04-15 | — | — | WO | disclosed |