Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 7/20 | 0.38 |
| ▸ | JAK3 | P52333 | 7/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 4/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23216990 | 0.77 | HPGD (0.40) | JAK2JAK3KCNQ3KCNQ2PIK3CD | |
| SCHEMBL17657041 | 0.71 | PIK3CG (0.45) | JAK2JAK3PIK3CDPIK3CGPIK3R2 | |
| SCHEMBL31061409 | 0.71 | IRAK4 (0.40) | JAK2JAK3PIK3CDPIK3CGPIK3R2 | |
| SCHEMBL7511248 | 0.71 | PARP1 (0.44) | HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL30267250 | 0.71 | JAK2 (0.54) | JAK2JAK3IRAK4 | |
| SCHEMBL462895 | 0.70 | HPGD (0.41) | PIK3CDPIK3CGIRAK4HPGDSMN1; SMN2 | |
| SCHEMBL22102607 | 0.70 | NTRK1 (0.51) | PIK3CDPIK3CGIRAK4HPGDSMN1; SMN2 | |
| SCHEMBL26247268 | 0.70 | APOBEC3A (0.41) | JAK2JAK3KCNQ3KCNQ2PIK3CD | |
| SCHEMBL17460390 | 0.69 | HPGD (0.42) | JAK2JAK3KCNQ3KCNQ2IRAK4 | |
| SCHEMBL29359724 | 0.68 | HTR6 (0.49) | KCNQ3KCNQ2PIK3CDPIK3CGIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041259-A1 | FEEDER-BASED AND FEEDER-FREE STEM CELL CULTURE SYSTEMS FOR STRATIFIED EPITHELIAL STEM CELLS, AND USES RELATED THERETO | University of Houston System (US) | 2022-08-17 | — | — | EP | disclosed |
| WO-2021072238-A1 | FEEDER-BASED AND FEEDER-FREE STEM CELL CULTURE SYSTEMS FOR STRATIFIED EPITHELIAL STEM CELLS, AND USES RELATED THERETO | UNIVERSITY OF HOUSTON SYSTEM (US) | 2021-04-15 | — | — | WO | disclosed |