Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 2/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 4/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 3/20 | 0.35 |
| ▸ | JAK3 | P52333 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23216990 | 0.79 | HPGD (0.40) | KCNQ3KCNQ2L3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL25261273 | 0.77 | KCNQ3 (0.43) | APOBEC3AAPOBEC3GKCNQ3KCNQ2L3MBTL1 | |
| SCHEMBL16619547 | 0.75 | PIK3CG (0.45) | APOBEC3AAPOBEC3GJAK2JAK3PIK3CG | |
| SCHEMBL3714513 | 0.75 | PIK3CG (0.51) | APOBEC3AAPOBEC3GL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL23728529 | 0.75 | APOBEC3A (0.45) | APOBEC3AAPOBEC3GKCNQ3KCNQ2L3MBTL1 | |
| SCHEMBL30028953 | 0.75 | KCNQ3 (0.38) | KCNQ3KCNQ2L3MBTL1IRAK4PPARG | |
| SCHEMBL29079557 | 0.75 | KCNQ3 (0.34) | APOBEC3AAPOBEC3GKCNQ3KCNQ2L3MBTL1 | |
| SCHEMBL29939215 | 0.74 | CYP11B2 (0.37) | APOBEC3AAPOBEC3GKCNQ3KCNQ2JAK2 | |
| SCHEMBL18208430 | 0.74 | PIK3CG (0.44) | APOBEC3AAPOBEC3GJAK2JAK3PIK3CG | |
| SCHEMBL26172231 | 0.73 | HTR6 (0.53) | APOBEC3AAPOBEC3GKCNQ3KCNQ2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230270751-A1 | BENZODIAZEPINE DERIVATIVES USEFUL IN TREATING A RESPIRATORY SYNCYTIAL VIRUS INFECTION | PFIZER INC. | 2023-08-31 | — | — | US | disclosed |
| US-20230270751-A1 | BENZODIAZEPINE DERIVATIVES USEFUL IN TREATING A RESPIRATORY SYNCYTIAL VIRUS INFECTION | PFIZER INC. | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230270751-A1 | BENZODIAZEPINE DERIVATIVES USEFUL IN TREATING A RESPIRATORY SYNCYTIAL VIRUS INFECTION | CNR1, CNR2, SIGMAR1 | APOBEC3A 4339/4885APOBEC3G 4510/4885KCNQ3 617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.