Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CFD | P00746 | 6/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | SLC26A3 | P40879 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30010173 | 0.90 | CFD (0.39) | DUSP3PTPN5PTPN11CTDSP1MEN1 | |
| SCHEMBL23217835 | 0.90 | CFD (0.39) | DUSP3PTPN5PTPN11CTDSP1MEN1 | |
| SCHEMBL23217842 | 0.90 | KCNA3 (0.41) | DUSP3PTPN5PTPN11CTDSP1MEN1 | |
| SCHEMBL30010388 | 0.90 | KCNA3 (0.41) | DUSP3PTPN5PTPN11CTDSP1MEN1 | |
| SCHEMBL23241696 | 0.90 | L3MBTL1 (0.37) | DUSP3PTPN5PTPN11CTDSP1L3MBTL1 | |
| SCHEMBL30009863 | 0.90 | L3MBTL1 (0.37) | DUSP3PTPN5PTPN11CTDSP1L3MBTL1 | |
| SCHEMBL30010445 | 0.89 | DUSP3 (0.37) | DUSP3PTPN5PTPN11CTDSP1L3MBTL1 | |
| SCHEMBL30010464 | 0.87 | CFD (0.38) | DUSP3PTPN5PTPN11CTDSP1MEN1 | |
| SCHEMBL23217640 | 0.87 | CFD (0.38) | DUSP3PTPN5PTPN11CTDSP1MEN1 | |
| SCHEMBL21437621 | 0.87 | DUSP3 (0.43) | DUSP3PTPN5PTPN11CTDSP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072156-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |