Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 14/20 | 0.60 |
| ▸ | F11 | P03951 | 3/20 | 0.38 |
| ▸ | TPSB2 | P20231 | 3/20 | 0.38 |
| ▸ | BAX | Q07812 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30010280 | 1.00 | CFD (0.60) | CFDF11TPSB2BAXALDH1A1 | |
| SCHEMBL29672986 | 0.90 | CFD (0.73) | CFDF11TPSB2 | |
| SCHEMBL29672981 | 0.90 | CFD (0.73) | CFDF11TPSB2 | |
| SCHEMBL23217512 | 0.90 | CFD (0.73) | CFDF11TPSB2 | |
| SCHEMBL30010615 | 0.87 | CFD (0.55) | CFDF11TPSB2BAXALDH1A1 | |
| SCHEMBL23217449 | 0.87 | CFD (0.55) | CFDF11TPSB2BAXALDH1A1 | |
| SCHEMBL23217192 | 0.86 | CFD (0.53) | CFDBAXALDH1A1MAPTTBXAS1 | |
| SCHEMBL23217613 | 0.86 | CFD (0.53) | CFDBAXALDH1A1MAPTTBXAS1 | |
| SCHEMBL29672942 | 0.86 | CFD (0.53) | CFDBAXALDH1A1MAPTTBXAS1 | |
| SCHEMBL30010424 | 0.86 | CFD (0.53) | CFDBAXALDH1A1MAPTTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041717-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |
| CN-114555570-A | Oral complement factor D inhibitors | 拜奥克里斯特制药公司 | 2022-05-27 | — | — | CN | disclosed |
| WO-2021072156-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |
| WO-2021072156-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |