Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 20/20 | 0.73 |
| ▸ | TPSB2 | P20231 | 9/20 | 0.48 |
| ▸ | F11 | P03951 | 9/20 | 0.48 |
| ▸ | PLG | P00747 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.41 |
| ▸ | F7 | P08709 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F9 | P00740 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29672981 | 1.00 | CFD (0.73) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL29672986 | 1.00 | CFD (0.73) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL30010280 | 0.90 | CFD (0.60) | CFDTPSB2F11 | |
| SCHEMBL23217627 | 0.90 | CFD (0.60) | CFDTPSB2F11 | |
| SCHEMBL29672967 | 0.85 | CFD (0.69) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL23217587 | 0.85 | CFD (0.69) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL21438021 | 0.85 | CFD (1.00) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL23217847 | 0.84 | CFD (0.67) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL23217514 | 0.84 | CFD (0.64) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL29672984 | 0.84 | CFD (0.67) | CFDTPSB2F11PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041717-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |
| CN-114555570-A | Oral complement factor D inhibitors | 拜奥克里斯特制药公司 | 2022-05-27 | — | — | CN | disclosed |
| WO-2021072156-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |
| WO-2021072156-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |