Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23217980 | 0.80 | OPRM1 (0.33) | OPRM1MPO | |
| SCHEMBL23218008 | 0.71 | OPRM1 (0.46) | OPRM1MPO | |
| SCHEMBL30753861 | 0.66 | LATS1 (0.35) | — | |
| SCHEMBL30753862 | 0.66 | LATS1 (0.35) | — | |
| SCHEMBL23217973 | 0.66 | OPRM1 (0.43) | OPRM1MPO | |
| SCHEMBL23225647 | 0.65 | OPRM1 (0.46) | OPRM1MPO | |
| SCHEMBL23225646 | 0.64 | OPRM1 (0.45) | OPRM1MPO | |
| SCHEMBL23225605 | 0.63 | OPRM1 (0.44) | OPRM1MPO | |
| SCHEMBL23225723 | 0.61 | OPRM1 (0.45) | OPRM1MPO | |
| Verdiperstat SCHEMBL23225670 | 0.60 | MPO (0.58) | OPRM1MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072140-A1 | PRODRUGS OF MYELOPEROXIDASE INHIBITORS | BIOHAVEN THERAPEUTICS LTD. (US) | 2021-04-15 | — | — | WO | disclosed |