Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 7/20 | 0.43 |
| ▸ | F11 | P03951 | 5/20 | 0.43 |
| ▸ | TPSB2 | P20231 | 5/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23218068 | 0.93 | CFD (0.51) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL29591349 | 0.93 | CFD (0.51) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL23218061 | 0.89 | PTGER4 (0.43) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL23218163 | 0.86 | CFD (0.52) | CFDF11TPSB2ANO1PTGER4 | |
| SCHEMBL29592750 | 0.86 | CFD (0.52) | CFDF11TPSB2ANO1PTGER4 | |
| SCHEMBL23229010 | 0.86 | CFD (0.52) | CFDF11TPSB2ANO1PTGER4 | |
| SCHEMBL23218377 | 0.86 | CFD (0.52) | CFDF11TPSB2ANO1PTGER4 | |
| SCHEMBL29339604 | 0.85 | P2RX3 (0.42) | ANO1PTGER4MTNR1AMTNR1B | |
| SCHEMBL23218533 | 0.85 | CFD (0.43) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL23219215 | 0.85 | CFD (0.52) | CFDF11TPSB2ANO1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |