Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 19/20 | 0.56 |
| ▸ | TPSB2 | P20231 | 5/20 | 0.43 |
| ▸ | F11 | P03951 | 5/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29592511 | 1.00 | CFD (0.56) | CFDTPSB2F11KLKB1PLG | |
| SCHEMBL29852433 | 0.89 | CFD (0.47) | CFDTPSB2F11KLKB1PLG | |
| SCHEMBL23219037 | 0.89 | CFD (0.47) | CFDTPSB2F11KLKB1PLG | |
| SCHEMBL29591424 | 0.87 | CFD (0.61) | CFDTPSB2F11KLKB1PLG | |
| SCHEMBL21437245 | 0.87 | CFD (0.57) | CFDTPSB2F11KLKB1PLG | |
| SCHEMBL23229020 | 0.87 | CFD (0.61) | CFDTPSB2F11KLKB1PLG | |
| SCHEMBL23218863 | 0.84 | CFD (0.61) | CFDTPSB2F11KLKB1PLG | |
| SCHEMBL29852776 | 0.84 | CFD (0.61) | CFDTPSB2F11KLKB1PLG | |
| SCHEMBL23219188 | 0.82 | CFD (0.53) | CFDTPSB2F11KLKB1PLG | |
| SCHEMBL29853137 | 0.82 | CFD (0.53) | CFDTPSB2F11KLKB1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |