Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 8/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | TPSB2 | P20231 | 6/20 | 0.38 |
| ▸ | F11 | P03951 | 5/20 | 0.38 |
| ▸ | ICMT | O60725 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 2/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29852706 | 1.00 | CFD (0.49) | CFDTBXAS1TPSB2F11ICMT | |
| SCHEMBL23219007 | 0.93 | CFD (0.47) | CFDTBXAS1TPSB2F11ICMT | |
| SCHEMBL29852422 | 0.93 | CFD (0.47) | CFDTBXAS1TPSB2F11ICMT | |
| SCHEMBL29122273 | 0.92 | CFD (0.46) | CFDTBXAS1TPSB2F11ICMT | |
| SCHEMBL23219243 | 0.90 | CFD (0.62) | CFDTBXAS1TPSB2F11ICMT | |
| SCHEMBL23229271 | 0.90 | CFD (0.51) | CFDTBXAS1TPSB2F11ICMT | |
| SCHEMBL29852710 | 0.90 | CFD (0.51) | CFDTBXAS1TPSB2F11ICMT | |
| SCHEMBL29852728 | 0.90 | CFD (0.51) | CFDTBXAS1TPSB2F11ICMT | |
| SCHEMBL29853182 | 0.90 | CFD (0.62) | CFDTBXAS1TPSB2F11ICMT | |
| SCHEMBL23219207 | 0.90 | CFD (0.55) | CFDTBXAS1TPSB2F11ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |
| CN-114502168-A | Oral complement factor D inhibitors | 拜奥克里斯特制药公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |