Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 4/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | F11 | P03951 | 3/20 | 0.35 |
| ▸ | TPSB2 | P20231 | 2/20 | 0.35 |
| ▸ | ICMT | O60725 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29852422 | 1.00 | CFD (0.47) | CFDTBXAS1F11TPSB2ICMT | |
| SCHEMBL29122273 | 0.93 | CFD (0.46) | CFDTBXAS1F11TPSB2ICMT | |
| SCHEMBL29852706 | 0.93 | CFD (0.49) | CFDTBXAS1F11TPSB2ICMT | |
| SCHEMBL23218752 | 0.93 | CFD (0.49) | CFDTBXAS1F11TPSB2ICMT | |
| SCHEMBL23219207 | 0.92 | CFD (0.55) | CFDTBXAS1F11TPSB2ICMT | |
| SCHEMBL29852913 | 0.92 | CFD (0.55) | CFDTBXAS1F11TPSB2ICMT | |
| SCHEMBL29340041 | 0.90 | CFD (0.46) | CFDTBXAS1F11TPSB2ICMT | |
| SCHEMBL23218754 | 0.89 | CFD (0.46) | CFDF11TPSB2ICMTPOLB | |
| SCHEMBL29592077 | 0.89 | CFD (0.46) | CFDF11TPSB2ICMTPOLB | |
| SCHEMBL29122667 | 0.89 | CFD (0.44) | CFDTBXAS1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502168-A | Oral complement factor D inhibitors | 拜奥克里斯特制药公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |