Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29853146 | 1.00 | CFD (0.37) | CFDTBXAS1PPARDHTTHSD17B10 | |
| SCHEMBL23218498 | 0.95 | CFD (0.39) | CFDTBXAS1PPARDHTTHSD17B10 | |
| SCHEMBL29852769 | 0.95 | CFD (0.39) | CFDTBXAS1PPARDHTTHSD17B10 | |
| SCHEMBL29852523 | 0.92 | CFD (0.37) | CFDTBXAS1PPARDHTTHSD17B10 | |
| SCHEMBL23219128 | 0.92 | CFD (0.37) | CFDTBXAS1PPARDHTTHSD17B10 | |
| SCHEMBL23218474 | 0.89 | CFD (0.47) | CFDTBXAS1HTR4MAP4K1SYK | |
| SCHEMBL29852461 | 0.89 | CFD (0.47) | CFDTBXAS1HTR4MAP4K1SYK | |
| SCHEMBL23218596 | 0.86 | CFD (0.37) | CFDTBXAS1PPARDHTTHSD17B10 | |
| SCHEMBL29852582 | 0.86 | CFD (0.37) | CFDTBXAS1PPARDHTTHSD17B10 | |
| SCHEMBL23219205 | 0.86 | CFD (0.41) | CFDTBXAS1PPARDHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502168-A | Oral complement factor D inhibitors | 拜奥克里斯特制药公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |