Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29852724 | 1.00 | CFD (0.41) | CFDTBXAS1DHFRMAPK1KDM4E | |
| SCHEMBL29121929 | 0.90 | CFD (0.40) | CFDTBXAS1MAPK1KDM4EALDH1A1 | |
| SCHEMBL29852769 | 0.89 | CFD (0.39) | CFDTBXAS1MAPK1KDM4EALDH1A1 | |
| SCHEMBL23218498 | 0.89 | CFD (0.39) | CFDTBXAS1MAPK1KDM4EALDH1A1 | |
| SCHEMBL23219128 | 0.86 | CFD (0.37) | CFDTBXAS1MAPK1PPARDHSD17B10 | |
| SCHEMBL23218774 | 0.86 | CFD (0.37) | CFDTBXAS1MAPK1KDM4EALDH1A1 | |
| SCHEMBL29852523 | 0.86 | CFD (0.37) | CFDTBXAS1MAPK1PPARDHSD17B10 | |
| SCHEMBL29853146 | 0.86 | CFD (0.37) | CFDTBXAS1MAPK1KDM4EALDH1A1 | |
| SCHEMBL23218596 | 0.85 | CFD (0.37) | CFDTBXAS1MAPK1PPARDHSD17B10 | |
| SCHEMBL29852582 | 0.85 | CFD (0.37) | CFDTBXAS1MAPK1PPARDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502168-A | Oral complement factor D inhibitors | 拜奥克里斯特制药公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |