Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | CFD | P00746 | 4/20 | 0.39 |
| ▸ | PLG | P00747 | 2/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29852478 | 1.00 | MTNR1A (0.40) | MTNR1AMTNR1BCFDPLGPLAU | |
| SCHEMBL23219076 | 0.96 | CFD (0.42) | MTNR1AMTNR1BCFDPLGPLAU | |
| SCHEMBL29592714 | 0.96 | CFD (0.42) | MTNR1AMTNR1BCFDPLGPLAU | |
| SCHEMBL23218455 | 0.86 | CFD (0.51) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL29592745 | 0.84 | CFD (0.51) | MTNR1AMTNR1BCFDPLGPLAU | |
| SCHEMBL23218571 | 0.84 | CFD (0.51) | MTNR1AMTNR1BCFDPLGPLAU | |
| SCHEMBL29852750 | 0.80 | CFD (0.42) | MTNR1AMTNR1BCFDPLGPLAU | |
| SCHEMBL23218913 | 0.80 | CFD (0.42) | MTNR1AMTNR1BCFDPLGPLAU | |
| SCHEMBL29592096 | 0.80 | CFD (0.54) | MTNR1AMTNR1BCFDPLGPLAU | |
| SCHEMBL23218533 | 0.79 | CFD (0.43) | MTNR1AMTNR1BCFDPLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |