Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 14/20 | 0.47 |
| ▸ | F11 | P03951 | 10/20 | 0.45 |
| ▸ | TPSB2 | P20231 | 9/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23218760 | 0.93 | CFD (0.54) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL29853224 | 0.93 | CFD (0.54) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL23218312 | 0.88 | CFD (0.59) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL23219073 | 0.86 | CFD (0.47) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL29852722 | 0.86 | CFD (0.47) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL23218366 | 0.86 | CFD (0.49) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL23218858 | 0.86 | CFD (0.54) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL29853271 | 0.86 | CFD (0.54) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL23218676 | 0.86 | CFD (0.48) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL29852445 | 0.86 | CFD (0.48) | CFDF11TPSB2KLKB1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |