Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 11/20 | 0.51 |
| ▸ | TPSB2 | P20231 | 9/20 | 0.51 |
| ▸ | F11 | P03951 | 9/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | ICMT | O60725 | 6/20 | 0.36 |
| ▸ | PLG | P00747 | 2/20 | 0.34 |
| ▸ | PLAU | P00749 | 2/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.34 |
| ▸ | F7 | P08709 | 2/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F9 | P00740 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29852748 | 1.00 | CFD (0.51) | CFDTPSB2F11TBXAS1ICMT | |
| SCHEMBL23229109 | 1.00 | CFD (0.51) | CFDTPSB2F11TBXAS1ICMT | |
| SCHEMBL29852710 | 0.94 | CFD (0.51) | CFDTPSB2F11TBXAS1ICMT | |
| SCHEMBL29852728 | 0.94 | CFD (0.51) | CFDTPSB2F11TBXAS1ICMT | |
| SCHEMBL23229271 | 0.94 | CFD (0.51) | CFDTPSB2F11TBXAS1ICMT | |
| SCHEMBL23219140 | 0.90 | CFD (0.63) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL29852900 | 0.90 | CFD (0.63) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL23219186 | 0.90 | CFD (0.63) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL23218752 | 0.89 | CFD (0.49) | CFDTPSB2F11TBXAS1ICMT | |
| SCHEMBL29852706 | 0.89 | CFD (0.49) | CFDTPSB2F11TBXAS1ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |