Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 7/20 | 0.43 |
| ▸ | TPSB2 | P20231 | 4/20 | 0.37 |
| ▸ | F11 | P03951 | 3/20 | 0.37 |
| ▸ | PLG | P00747 | 2/20 | 0.37 |
| ▸ | PLAU | P00749 | 2/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | ICMT | O60725 | 2/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NMT1 | P30419 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29852818 | 1.00 | CFD (0.43) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL23219138 | 0.95 | CFD (0.42) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL29852616 | 0.95 | CFD (0.42) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL29853066 | 0.92 | CFD (0.40) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL23219209 | 0.92 | CFD (0.40) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL23219028 | 0.88 | CFD (0.39) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL29853069 | 0.88 | CFD (0.39) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL23228977 | 0.86 | CFD (0.37) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL23229178 | 0.86 | CFD (0.37) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL23219170 | 0.85 | CFD (0.46) | CFDTPSB2F11PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502168-A | Oral complement factor D inhibitors | 拜奥克里斯特制药公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |