Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 7/20 | 0.37 |
| ▸ | TPSB2 | P20231 | 5/20 | 0.35 |
| ▸ | F11 | P03951 | 4/20 | 0.35 |
| ▸ | PLG | P00747 | 2/20 | 0.35 |
| ▸ | PLAU | P00749 | 2/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | HCK | P08631 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23228977 | 0.89 | CFD (0.37) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL29853066 | 0.87 | CFD (0.40) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL23219209 | 0.87 | CFD (0.40) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL23219193 | 0.86 | CFD (0.43) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL29852818 | 0.86 | CFD (0.43) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL29853069 | 0.84 | CFD (0.39) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL23219028 | 0.84 | CFD (0.39) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL29852616 | 0.83 | CFD (0.42) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL23219138 | 0.83 | CFD (0.42) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL23219231 | 0.80 | PLG (0.46) | CFDTPSB2F11PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |