Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 12/20 | 0.50 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29852530 | 1.00 | CFD (0.50) | CFDDPP4TBXAS1MEN1POLB | |
| SCHEMBL29853186 | 0.92 | CFD (0.42) | CFDDPP4TBXAS1MEN1POLB | |
| SCHEMBL23229274 | 0.92 | CFD (0.42) | CFDDPP4TBXAS1MEN1POLB | |
| SCHEMBL21437732 | 0.91 | CFD (0.58) | CFDDPP4TBXAS1MEN1POLB | |
| SCHEMBL23218863 | 0.90 | CFD (0.61) | CFD | |
| SCHEMBL29852776 | 0.90 | CFD (0.61) | CFD | |
| SCHEMBL23219037 | 0.86 | CFD (0.47) | CFDDPP4TBXAS1MAPT | |
| SCHEMBL29852433 | 0.86 | CFD (0.47) | CFDDPP4TBXAS1MAPT | |
| SCHEMBL29852794 | 0.85 | CFD (0.41) | CFDTBXAS1MEN1POLBHPGD | |
| SCHEMBL23217566 | 0.85 | CFD (0.45) | CFDDPP4TBXAS1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |