Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | BCR | P11274 | 1/20 | 0.30 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21938544 | 0.77 | TNK2 (0.33) | SMN1; SMN2 | |
| SCHEMBL29297663 | 0.69 | SMN1; SMN2 (0.37) | SMN1; SMN2ABL1BCR | |
| SCHEMBL10098691 | 0.69 | MAPK7 (0.56) | MAPK7 | |
| SCHEMBL3542184 | 0.68 | SMN1; SMN2 (0.40) | SMN1; SMN2MAPK7ABL1BCR | |
| SCHEMBL6844626 | 0.67 | STK4 (0.49) | SMN1; SMN2ABL1BCR | |
| SCHEMBL20628431 | 0.67 | STK3 (0.57) | SMN1; SMN2MAPK7ABL1PTK2 | |
| SCHEMBL22658779 | 0.66 | PTK2 (0.59) | PTK2 | |
| SCHEMBL19457452 | 0.66 | PIK3CD (0.56) | MAPK7 | |
| SCHEMBL30131807 | 0.66 | PIK3CD (0.56) | MAPK7 | |
| SCHEMBL29517219 | 0.66 | PTK2 (0.59) | PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10975092-B2 | Pyrimidine seven-membered-ring compounds, preparation method therefor, pharmaceutical composition thereof, and uses thereof | ANHUI NEW STAR PHARMACEUTICAL DEVELOPMENT CO., LTD. (CN) | 2021-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10975092-B2 | Pyrimidine seven-membered-ring compounds, preparation method therefor, pharmaceutical composition thereof, and uses thereof | MST1, STK11, MSTN | SMN1; SMN2 517/4885MAPK7 112/4885ABL1 1204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.