SCHEMBL23219391

SCHEMBL23219391

COc1ccc(N(c2ccc(OC)cc2)c2ccc(-c3ccc(N(c4ccc(-c5ccc(/C=C(\C#N)C(=O)O)s5)cc4)c4ccc(-c5ccc(/C=C(\C#N)C(=O)O)s5)cc4)cc3)cc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.72
APP P05067 5/20 0.61
SLC16A3 O15427 4/20 0.50
SLC16A1 P53985 4/20 0.50
ATM Q13315 1/20 0.44
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7006744 1.00 MAPT (0.72) MAPTAPPSLC16A3SLC16A1ATM
SCHEMBL7006862 0.97 MAPT (0.78) MAPTAPPSLC16A3SLC16A1ATM
SCHEMBL15859155 0.92 MAPT (0.62) MAPTAPPATMALDH1A1
SCHEMBL15859153 0.92 MAPT (0.62) MAPTAPPATMALDH1A1
SCHEMBL14730340 0.92 MAPT (0.62) MAPTAPPATMALDH1A1
SCHEMBL14962663 0.91 MAPT (0.70) MAPTAPPSLC16A3SLC16A1ATM
SCHEMBL14646320 0.89 MAPT (0.58) MAPTAPPSLC16A3SLC16A1ATM
SCHEMBL21065539 0.88 MAPT (0.63) MAPTAPPSLC16A3SLC16A1ATM
SCHEMBL23219386 0.88 MAPT (0.61) MAPTAPPSLC16A3SLC16A1ALDH1A1
SCHEMBL7006742 0.88 MAPT (0.61) MAPTAPPSLC16A3SLC16A1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10978255-B2 Bichromic bipodal triphenylamine-based dyes with high photo-electron conversion at low light intensities KOIVISTO BRYAN (CA) 2021-04-13 US disclosed