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Sugi Predict / Compounds / SCHEMBL23219386

SCHEMBL23219386

SCHEMBL23219386

COc1ccc(N(c2ccc(OC)cc2)c2ccc(-c3ccc(-c4ccc(N(c5ccc(/C=C(\C#N)C(=O)O)cc5)c5ccc(/C=C(\C#N)C(=O)O)cc5)cc4)s3)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 1/20 0.61
▸ SLC16A3 O15427 1/20 0.51
▸ SLC16A1 P53985 1/20 0.51
▸ APP P05067 2/20 0.51
▸ ALDH1A1 P00352 1/20 0.48
▸ CISD1 Q9NZ45 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7006742 1.00 MAPT (0.61) MAPTSLC16A3SLC16A1APPALDH1A1
SCHEMBL7008415 0.91 SLC16A3 (0.57) SLC16A3SLC16A1ALDH1A1CISD1
SCHEMBL15664267 0.89 MAPT (0.50) MAPTSLC16A3SLC16A1APPALDH1A1
SCHEMBL15664268 0.89 MAPT (0.50) MAPTSLC16A3SLC16A1APPALDH1A1
SCHEMBL7006862 0.89 MAPT (0.78) MAPTSLC16A3SLC16A1APPALDH1A1
SCHEMBL7006744 0.88 MAPT (0.72) MAPTSLC16A3SLC16A1APPALDH1A1
SCHEMBL23219391 0.88 MAPT (0.72) MAPTSLC16A3SLC16A1APPALDH1A1
SCHEMBL7006739 0.87 MAPT (0.65) MAPTSLC16A3SLC16A1APPALDH1A1
SCHEMBL12294129 0.87 MAPT (0.78) MAPTSLC16A3SLC16A1APPALDH1A1
SCHEMBL7007659 0.87 MAPT (0.78) MAPTSLC16A3SLC16A1APPALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10978255-B2 Bichromic bipodal triphenylamine-based dyes with high photo-electron conversion at low light intensities KOIVISTO BRYAN (CA) 2021-04-13 — — US disclosed