SCHEMBL7006744

SCHEMBL7006744

COc1ccc(N(c2ccc(OC)cc2)c2ccc(-c3ccc(-c4ccc(/C=C(\C#N)C(=O)O)s4)cc3)cc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.72
APP P05067 5/20 0.61
SLC16A3 O15427 4/20 0.50
SLC16A1 P53985 4/20 0.50
ATM Q13315 1/20 0.44
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23219391 1.00 MAPT (0.72) MAPTAPPSLC16A3SLC16A1ATM
SCHEMBL7006862 0.97 MAPT (0.78) MAPTAPPSLC16A3SLC16A1ATM
SCHEMBL15859155 0.92 MAPT (0.62) MAPTAPPATMALDH1A1
SCHEMBL15859153 0.92 MAPT (0.62) MAPTAPPATMALDH1A1
SCHEMBL14730340 0.92 MAPT (0.62) MAPTAPPATMALDH1A1
SCHEMBL14962663 0.91 MAPT (0.70) MAPTAPPSLC16A3SLC16A1ATM
SCHEMBL14646320 0.89 MAPT (0.58) MAPTAPPSLC16A3SLC16A1ATM
SCHEMBL21065539 0.88 MAPT (0.63) MAPTAPPSLC16A3SLC16A1ATM
SCHEMBL23219386 0.88 MAPT (0.61) MAPTAPPSLC16A3SLC16A1ALDH1A1
SCHEMBL7006742 0.88 MAPT (0.61) MAPTAPPSLC16A3SLC16A1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8183393-B2 Dye compound and dye-sensitized solar cell ACADEMIA SINICA (TW) 2012-05-22 US disclosed
US-20100076205-A1 DYE COMPOUND AND DYE-SENSITIZED SOLAR CELL ACADEMIA SINICA (TW) 2010-03-25 US disclosed
US-20100076205-A1 DYE COMPOUND AND DYE-SENSITIZED SOLAR CELL ACADEMIA SINICA (TW) 2010-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100076205-A1 DYE COMPOUND AND DYE-SENSITIZED SOLAR CELL CRY1, DSG1, CRY2 MAPT 4399/4885APP 2553/4885SLC16A3 3316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.