SCHEMBL2321948

SCHEMBL2321948

B.c1ccc(-c2ccnc(-c3ccccc3)c2-c2ccccc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCNA2 P20248 5/20 0.44
CDK2 P24941 5/20 0.44
CDK5 Q00535 2/20 0.42
CDK7 P50613 2/20 0.42
IKBKB O14920 1/20 0.42
CHUK O15111 1/20 0.42
DAPK3 O43293 1/20 0.42
JAK2 O60674 1/20 0.42
PRKD3 O94806 1/20 0.42
MAP4K4 O95819 1/20 0.42
PAK4 O96013 1/20 0.42
CSF1R P07333 1/20 0.42
RET P07949 1/20 0.42
IGF1R P08069 1/20 0.42
FGFR1 P11362 1/20 0.42
PRKACA P17612 1/20 0.42
FLT1 P17948 1/20 0.42
LTK P29376 1/20 0.42
GRK5 P34947 1/20 0.42
KDR P35968 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL996432 0.98 CCNA2 (0.45) CCNA2CDK2CDK5CDK7IKBKB
SCHEMBL8444233 0.96 CCNA2 (0.44) CCNA2CDK2CDK5CDK7IKBKB
SCHEMBL4618932 0.96 CCNA2 (0.44) CCNA2CDK2CDK5CDK7IKBKB
SCHEMBL321472 0.96 CCNA2 (0.44) CCNA2CDK2CDK5CDK7IKBKB
Boric Acid SCHEMBL28009850 0.90 CCNA2 (0.41) CCNA2CDK2CDK5CDK7IKBKB
SCHEMBL30335027 0.90 ADORA2A (0.50) CCNA2CDK2PRKD3MAP4K4FGFR1
Thiophene SCHEMBL28457018 0.87 CCNA2 (0.39) CCNA2CDK2CDK5CDK7IKBKB
SCHEMBL18050348 0.87 CYP3A4 (0.47) CCNA2CDK2CDK5PTGS1PTGS2
SCHEMBL28592103 0.87 CCNA2 (0.39) CCNA2CDK2CDK5CDK7IKBKB
SCHEMBL28317500 0.87 CDK2 (0.52) CCNA2CDK2CDK5CDK7IKBKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2352876-B1 TREATED TEXTILE MATERIAL FOR USE IN AQUATIC ENVIRONMENTS BASF SE (DE) 2012-12-12 EP claimed
CN-102272376-A Treated textile material for aquatic environments 2011-12-07 CN claimed
US-20110217348-A1 TREATED TEXTILE MATERIAL FOR USE IN AQUATIC ENVIRONMENTS BASF SE (DE) 2011-09-08 US claimed
EP-2352876-A1 TREATED TEXTILE MATERIAL FOR USE IN AQUATIC ENVIRONMENTS BASF SE (DE) 2011-08-10 EP claimed
WO-2010052153-A1 TREATED TEXTILE MATERIAL FOR USE IN AQUATIC ENVIRONMENTS BASF SE (DE) 2010-05-14 WO claimed
WO-2006087356-A2 SYNERGISTIC ANTIFOULING COMPOSITIONS COMPRISING (4-ISOPROPYLPYRIDINIO)METHYLDIPHENYLBORON JANSSEN PHARMACEUTICA N.V. (BE) 2006-08-24 WO claimed
CN-115298274-A Antifouling coating composition 中国涂料株式会社 2022-11-04 CN disclosed
EP-2352876-B1 TREATED TEXTILE MATERIAL FOR USE IN AQUATIC ENVIRONMENTS BASF SE (DE) 2012-12-12 EP disclosed
CN-102272376-A Treated textile material for aquatic environments 2011-12-07 CN disclosed
US-20110217348-A1 TREATED TEXTILE MATERIAL FOR USE IN AQUATIC ENVIRONMENTS BASF SE (DE) 2011-09-08 US disclosed
EP-2352876-A1 TREATED TEXTILE MATERIAL FOR USE IN AQUATIC ENVIRONMENTS BASF SE (DE) 2011-08-10 EP disclosed
CN-101094899-B Water-based curing type antifouling coating composition, antifouling coating film and underwater structure NIPPON PAINT CO LTD 2010-09-01 CN disclosed
WO-2010052153-A1 TREATED TEXTILE MATERIAL FOR USE IN AQUATIC ENVIRONMENTS BASF SE (DE) 2010-05-14 WO disclosed
CN-101094899-A Water-based curing type antifouling coating composition, antifouling coating film and underwater structure NIPPON PAINT CO LTD (JP) 2007-12-26 CN disclosed
WO-2006087356-A3 SYNERGISTIC ANTIFOULING COMPOSITIONS COMPRISING (4-ISOPROPYLPYRIDINIO)METHYLDIPHENYLBORON JANSSEN PHARMACEUTICA NV (BE) 2007-01-11 WO disclosed
WO-2006087356-A2 SYNERGISTIC ANTIFOULING COMPOSITIONS COMPRISING (4-ISOPROPYLPYRIDINIO)METHYLDIPHENYLBORON JANSSEN PHARMACEUTICA N.V. (BE) 2006-08-24 WO disclosed
WO-2006087356-A2 SYNERGISTIC ANTIFOULING COMPOSITIONS COMPRISING (4-ISOPROPYLPYRIDINIO)METHYLDIPHENYLBORON JANSSEN PHARMACEUTICA N.V. (BE) 2006-08-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110217348-A1 TREATED TEXTILE MATERIAL FOR USE IN AQUATIC ENVIRONMENTS C9, ADORA2B, C5 CCNA2 55/4885CDK2 930/4885CDK5 2824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.