SCHEMBL321472

SCHEMBL321472

[Ir].c1ccc(-c2ccnc(-c3ccccc3)c2-c2ccccc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCNA2 P20248 5/20 0.44
CDK2 P24941 5/20 0.44
CDK5 Q00535 2/20 0.42
CDK7 P50613 2/20 0.42
IKBKB O14920 1/20 0.42
CHUK O15111 1/20 0.42
DAPK3 O43293 1/20 0.42
JAK2 O60674 1/20 0.42
PRKD3 O94806 1/20 0.42
MAP4K4 O95819 1/20 0.42
PAK4 O96013 1/20 0.42
CSF1R P07333 1/20 0.42
RET P07949 1/20 0.42
IGF1R P08069 1/20 0.42
FGFR1 P11362 1/20 0.42
PRKACA P17612 1/20 0.42
FLT1 P17948 1/20 0.42
LTK P29376 1/20 0.42
GRK5 P34947 1/20 0.42
KDR P35968 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL996432 0.98 CCNA2 (0.45) CCNA2CDK2CDK5CDK7IKBKB
SCHEMBL2321948 0.96 CCNA2 (0.44) CCNA2CDK2CDK5CDK7IKBKB
SCHEMBL8444233 0.96 CCNA2 (0.44) CCNA2CDK2CDK5CDK7IKBKB
SCHEMBL4618932 0.96 CCNA2 (0.44) CCNA2CDK2CDK5CDK7IKBKB
Boric Acid SCHEMBL28009850 0.90 CCNA2 (0.41) CCNA2CDK2CDK5CDK7IKBKB
SCHEMBL30335027 0.90 ADORA2A (0.50) CCNA2CDK2PRKD3MAP4K4FGFR1
Thiophene SCHEMBL28457018 0.87 CCNA2 (0.39) CCNA2CDK2CDK5CDK7IKBKB
SCHEMBL28592103 0.87 CCNA2 (0.39) CCNA2CDK2CDK5CDK7IKBKB
SCHEMBL18050348 0.87 CYP3A4 (0.47) CCNA2CDK2CDK5PTGS1PTGS2
SCHEMBL28317500 0.87 CDK2 (0.52) CCNA2CDK2CDK5CDK7IKBKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118812589-A Trialkylphosphine oxide compound derivative and preparation method thereof 北京大学 2024-10-22 CN claimed
CN-118812589-A Trialkylphosphine oxide compound derivative and preparation method thereof 北京大学 2024-10-22 CN disclosed
EP-3901235-B1 ORGANIC ELECTROLUMINESCENT DEVICES AND METAL COMPLEX COMPOUNDS UDC IRELAND LTD (IE) 2023-11-15 EP disclosed
CN-114031555-B Organic compounds, mixtures, compositions and organic electronic devices containing naphtho [2,1-c ] acridines 广东聚华印刷显示技术有限公司 2023-10-31 CN disclosed
CN-112552173-B Preparation method of fluoro alkenyl ketone compound 山东领海生物科技有限公司 2022-11-15 CN disclosed
CN-112552173-B Preparation method of fluoro alkenyl ketone compound 山东领海生物科技有限公司 2022-11-15 CN disclosed
EP-3211057-B2 ORGANIC ELECTROLUMINESCENT DEVICES AND METAL COMPLEX COMPOUNDS UDC IRELAND LTD (IE) 2022-11-02 EP disclosed
US-20220344601-A1 Organic Electroluminescent Devices and Metal Complex Compounds UDC IRELAND LTD (IE) 2022-10-27 US disclosed
US-11393989-B2 Organic electroluminescent devices and metal complex compounds UDC IRELAND LIMITED (IE) 2022-07-19 US disclosed
CN-114031555-A Organic compounds containing naphtho [2,1-c ] acridine, mixtures, compositions and organic electronic devices 广东聚华印刷显示技术有限公司 2022-02-11 CN disclosed
US-20050164032-A1 Organic electroluminescent element FUJI PHOTO FILM CO., LTD. 2005-07-28 US disclosed
US-20050142383-A1 Organic electroluminescent device FUJI PHOTO FILM CO., LTD 2005-06-30 US disclosed
US-20050112407-A1 Organic electroluminescent device FUJI PHOTO FILM CO., LTD. 2005-05-26 US disclosed
WO-2004099339-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND PLATINUM COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 2004-11-18 WO disclosed
US-6783873-B2 METAL COMPLEX CANON KABUSHIKI KAISHA (JP) 2004-08-31 US disclosed
US-20040065544-A1 Organic electroluminescent device FUJI PHOTO FILM CO., LTD. 2004-04-08 US disclosed
US-20040053071-A1 Light emitting element and iridium complex FUJI PHOTO FILM CO., LTD. 2004-03-18 US disclosed
EP-1398363-A1 Light emitting element and iridium complex FUJI PHOTO FILM CO., LTD. (JP) 2004-03-17 EP disclosed
US-20030152802-A1 Metal coordination compound and organic liminescence device CANON KABUSHIKI KAISHA (JP) 2003-08-14 US disclosed
US-20030080342-A1 Light-emitting element and novel iridium complexes FUJI PHOTO FILM CO., LTD. 2003-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220344601-A1 Organic Electroluminescent Devices and Metal Complex Compounds EPCAM, TPR, L1CAM CCNA2 3682/4885CDK2 2150/4885CDK5 3783/4885
US-11393989-B2 Organic electroluminescent devices and metal complex compounds EPCAM, TPR, L1CAM CCNA2 3682/4885CDK2 2150/4885CDK5 3783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.