⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36821 | 0.84 | — | — | |
| SCHEMBL653853 | 0.84 | ALDH1A1 (0.46) | — | |
| SCHEMBL29958613 | 0.82 | CYP4F2 (0.44) | — | |
| Methane SCHEMBL21632462 | 0.82 | CYP4F2 (0.44) | — | |
| SCHEMBL27633249 | 0.82 | — | — | |
| SCHEMBL3344606 | 0.81 | ALDH1A1 (0.52) | — | |
| SCHEMBL9516554 | 0.81 | POLB (0.37) | — | |
| SCHEMBL297524 | 0.81 | — | — | |
| SCHEMBL2812400 | 0.80 | ALDH1A1 (0.46) | — | |
| SCHEMBL1359837 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946476-B2 | Process for the preparation of amino acid derivatives | UCB PHARMA GMBH (DE) | 2015-02-03 | — | — | US | disclosed |
| EP-2352721-B1 | NOVEL PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES | UCB PHARMA GMBH (DE) | 2013-03-27 | — | — | EP | disclosed |
| US-20110263899-A1 | Novel Process for the Preparation of Amino Acid Derivatives | UCB PHARMA GMBH (DE) | 2011-10-27 | — | — | US | disclosed |
| EP-2352721-A1 | NOVEL PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES | UCB Pharma GmbH (DE) | 2011-08-10 | — | — | EP | disclosed |
| WO-2010052011-A1 | NOVEL PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES | UCB PHARMA, S.A. (BE) | 2010-05-14 | — | — | WO | disclosed |
| EP-1268449-A4 | SUBSTITUTED PIPERIDINES AS MELANOCORTIN RECEPTOR AGONISTS | MERCK & CO INC (US) | 2004-09-15 | — | — | EP | disclosed |
| EP-1268449-A1 | SUBSTITUTED PIPERIDINES AS MELANOCORTIN RECEPTOR AGONISTS | Merck & Co., Inc. (US) | 2003-01-02 | — | — | EP | disclosed |
| US-6458790-B2 | DIETETICS; ANTIDABETIC AGENTS; SEXUAL DISRDERS | MERCK & CO., INC. | 2002-10-01 | — | — | US | disclosed |
| US-20020019523-A1 | Substituted piperidines as melanocortin receptor agonists | MERCK SHARP & DOHME CORP. | 2002-02-14 | — | — | US | disclosed |
| WO-2001070708-A1 | SUBSTITUTED PIPERIDINES AS MELANOCORTIN RECEPTOR AGONISTS | MERCK & CO., INC. (US) | 2001-09-27 | — | — | WO | disclosed |
| EP-0923563-A1 | 1,4-HETEROCYCLIC METALLPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008825-A1 | 1,4-HETEROCYCLIC METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |
| EP-0458325-A1 | Negative photosensitive composition and method for forming a resist pattern | Mitsubishi Chemical Corporation (JP) | 1991-11-27 | — | — | EP | disclosed |
| US-4188390-A | Antihypertensive 4-amino-2-[4-(1,4-benzodioxan-2-carbonyl) piperazin-1-yl or homopiperazin-1-yl]quinazolines | PFIZER INC. (US) | 1980-02-12 | — | — | US | disclosed |