Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | DGKA | P23743 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2784663 | 0.87 | TSHR (0.38) | POLBGAANPSR1CHRM2CHRM1 | |
| SCHEMBL7036698 | 0.87 | ALDH1A1 (0.42) | POLBGAANPSR1CHRM2CHRM1 | |
| SCHEMBL36866 | 0.83 | POLB (0.41) | POLBGAANPSR1CHRM2CHRM1 | |
| SCHEMBL2321956 | 0.81 | — | — | |
| SCHEMBL14507455 | 0.77 | ALDH1A1 (0.38) | POLBGAANPSR1CHRM2CHRM1 | |
| SCHEMBL19393389 | 0.77 | POLB (0.50) | POLBGAANPSR1CHRM2CHRM1 | |
| Ethylene Glycol SCHEMBL830063 | 0.77 | POLB (0.38) | POLBGAANPSR1CHRM2CHRM1 | |
| SCHEMBL29664486 | 0.77 | ALDH1A1 (0.38) | POLBGAANPSR1CHRM2CHRM1 | |
| SCHEMBL4258156 | 0.77 | POLB (0.48) | POLBGAANPSR1CHRM2CHRM1 | |
| SCHEMBL26784986 | 0.76 | KMT2A (0.46) | NPSR1CHRM2CHRM1CHRM3CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236624-B1 | SUBSTITUTED PHENYL ETHANOL AMINES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1993-08-11 | — | — | EP | disclosed |