Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 4/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866652 | 0.75 | SUV39H2 (0.45) | PTGS1PTGS2KDM4ENPC1RAB9A | |
| SCHEMBL12970576 | 0.73 | SMN1; SMN2 (0.73) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| Acetic Acid SCHEMBL16212577 | 0.70 | TLR9 (0.65) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| Acetic Acid SCHEMBL16212317 | 0.70 | SUV39H2 (0.53) | PTGS1PTGS2KDM4ENPC1RAB9A | |
| SCHEMBL16220801 | 0.70 | SUV39H2 (0.57) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL16212530 | 0.70 | TLR9 (0.69) | KDM4ENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL8866307 | 0.70 | SUV39H2 (0.46) | KDM4ENPC1RAB9AALDH1A1TP53 | |
| SCHEMBL8866424 | 0.69 | ALDH1A1 (0.46) | PTGS1PTGS2KDM4ENPC1RAB9A | |
| SCHEMBL16212288 | 0.69 | SUV39H2 (0.39) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL26526468 | 0.69 | PARP1 (0.46) | KDM4ENPC1RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10975073-B2 | Imaging methods using 2-hetaryl imidazol[1,2-a]pyridine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2021-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10975073-B2 | Imaging methods using 2-hetaryl imidazol[1,2-a]pyridine derivatives | HTR3D, PTGDR2, PTGIR | PTGS1 57/4885PTGS2 24/4885KDM4E 4358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.